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License and Acquisition Agreements - Regeneron License Agreement (Details) - Regeneron - USD ($)
$ in Thousands
1 Months Ended 12 Months Ended
Sep. 30, 2017
Dec. 31, 2020
Dec. 31, 2019
Dec. 31, 2018
Mar. 31, 2021
License Agreement          
License and Acquisition Agreements          
Upfront payment for exchange of rights $ 5,000        
Milestone payment to be paid upon regulatory milestone achievement   $ 7,500     $ 20,000
Research and development expense, Milestone   $ 7,500 $ 0 $ 0  
Uncured period which causes termination of the agreement, due to insolvency or bankruptcy or for material breach of the agreement by the other party that remains uncured 90 days        
Notice period to terminate the agreement under payment-related breaches 30 days        
Consecutive suspension of activities period for termination of agreement 12 months        
Period after which the agreement can be terminated 18 months        
Notice period to terminate the agreement 180 days        
Notice period to terminate the agreement after US marketing approval of the developed product 1 year        
Notice period to terminate the agreement if products are having safety concerns 3 months        
Clinical Supply Agreement          
License and Acquisition Agreements          
Research and development expense related to purchase of drug materials     $ 6,854 $ 1,835  
Maximum | License Agreement          
License and Acquisition Agreements          
Milestone payment to be paid upon regulatory milestone achievement $ 27,500