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License, Acquisition and Collaboration Agreements - Novo Nordisk License Agreement (Details) - USD ($)
$ in Thousands
1 Months Ended 3 Months Ended 6 Months Ended
Aug. 31, 2017
Jun. 30, 2020
Jun. 30, 2019
Jun. 30, 2020
Jun. 30, 2019
License and Acquisition Agreements          
Research and development   $ 22,324 $ 30,848 $ 43,225 $ 90,101
License Agreement | Novo Nordisk          
License and Acquisition Agreements          
Upfront payment for exchange of rights $ 1,500        
Research and development   $ 0 $ 0 $ 0 $ 0