CONSOLIDATED STATEMENTS OF OPERATIONS AND COMPREHENSIVE LOSS - USD ($) $ in Thousands	3 Months Ended
	Mar. 31, 2020	Mar. 31, 2019
Operating expenses:
Research and development	$ 20,901	$ 59,253
General and administrative	8,486	8,394
Total operating expenses	29,387	67,647
Loss from operations	(29,387)	(67,647)
Interest income	789	1,809
Loss before benefit for income taxes	(28,598)	(65,838)
Benefit for income taxes	2,179	17
Net loss	$ (26,419)	$ (65,821)
Net loss per share attributable to common shareholders—basic and diluted	$ (0.48)	$ (1.27)
Weighted average common shares outstanding—basic and diluted	55,322,690	51,758,353
Comprehensive loss:
Net loss	$ (26,419)	$ (65,821)
Other comprehensive income:
Unrealized gain on short-term investments and currency translation adjustments, net of tax	207	12
Total other comprehensive income	207	12
Total comprehensive loss	$ (26,212)	$ (65,809)