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Consolidated Statements of Operations and Comprehensive Loss - USD ($)
$ in Thousands
12 Months Ended
Dec. 31, 2024
Dec. 31, 2023
Dec. 31, 2022
Revenue:      
Total revenue $ 114,701 $ 0 $ 0
Operating expenses:      
Research and development 138,487 135,304 170,919
In process research and development 0 10,000 65
General and administrative 36,133 38,455 47,609
Total operating expenses 174,620 183,759 218,593
Loss from operations (59,919) (183,759) (218,593)
Other income (expense)      
Interest income 1,779 1,997 1,583
Interest expense (11,517) (13,511) (13,880)
Other income, net 14,022 15,456 1,512
Total other income (expense), net 4,284 3,942 (10,785)
Loss before provision for income taxes (55,635) (179,817) (229,378)
Provision for income taxes 893 0 0
Net loss (56,528) (179,817) (229,378)
Other comprehensive income (loss):      
Foreign currency translation 1,450 33 (544)
Unrealized income (loss) on marketable securities 89 191 (75)
Other comprehensive income (loss) 1,539 224 (619)
Comprehensive loss $ (54,989) $ (179,593) $ (229,997)
Net loss per share, basic (in dollars per share) $ (0.25) $ (1.18) $ (2.71)
Net loss per share, diluted (in dollars per share) $ (0.25) $ (1.18) $ (2.71)
Weighted average common shares outstanding, basic (in shares) 226,228,016 152,621,669 84,574,869
Weighted average common shares outstanding, diluted (in shares) 226,228,016 152,621,669 84,574,869
Revenue from sale of licenses      
Revenue:      
Total revenue $ 90,682 $ 0 $ 0
Revenue from contracts with collaborators      
Revenue:      
Total revenue $ 24,019 $ 0 $ 0