CONSOLIDATED BALANCE SHEETS - USD ($) $ in Thousands	Sep. 30, 2022	Dec. 31, 2021
Current assets:
Cash and cash equivalents	$ 133,075	$ 212,835
Marketable securities	210,580	40,159
Prepaid expenses and other current assets	13,957	12,325
Total current assets	357,612	265,319
Property and equipment, net	8,142	9,564
Operating lease right-of-use asset	20,319	25,442
Restricted cash	2,498	2,498
Other long-term assets	1,732	1,622
Total assets	390,303	304,445
Current liabilities:
Accounts payable	2,001	4,434
Accrued expenses	22,866	17,456
Operating lease liability	8,064	7,407
Short-term debt	805	1,577
Deferred revenue		33,193
Other current liabilities		230
Total current liabilities	33,736	64,297
Long-term portion of operating lease liability	13,535	19,652
Long-term debt	49,767	48,422
Total liabilities	97,038	132,371
Commitments and contingencies (Note 8)
Stockholders' equity:
Preferred stock, $0.001 par value; 10,000,000 shares authorized at September 30, 2022 and December 31, 2021; no shares issued and outstanding at September 30, 2022 and December 31, 2021
Common stock, $0.001 par value; 150,000,000 shares authorized; 51,660,854 and 35,209,099 shares issued and outstanding as of September 30, 2022 and December 31, 2021, respectively	52	35
Additional paid-in capital	765,526	548,204
Accumulated other comprehensive loss	(936)	(35)
Accumulated deficit	(471,377)	(376,130)
Total stockholders' equity	293,265	172,074
Total liabilities and stockholders' equity	$ 390,303	$ 304,445