X0508 4 2023-10-16 0 0001727196 Scholar Rock Holding Corp SRRK 0001253170 AKKARAJU SRINIVAS 628 MIDDLEFIELD ROAD PALO ALTO CA 94301 1 0 1 0 0 Common Stock 2023-10-16 4 P 0 2189781 6.85 A 6788609 I By Samsara BioCapital, L.P. Shares held by Samsara BioCapital LP ("Samsara LP"). The Reporting Person is a managing member of Samsara BioCapital GP, LLC, the general partner of Samsara LP. The Reporting Person disclaims beneficial ownership of these shares except to the extent of his pecuniary interest therein. /s/ Srinivas Akkaraju 2023-10-18