X0508 4 2023-12-14 0001727196 Scholar Rock Holding Corp SRRK 0001980298 Qatanani Mo 301 BINNEY STREET CAMBRIDGE MA 02142 0 1 0 0 SVP AND HEAD OF RESEARCH 0 Common Stock 2023-12-14 4 M 0 8437 10 A 105480 D Common Stock 2023-12-14 4 S 0 24662 18.1836 D 80818 D Stock Option (Right to Buy) 10 2023-12-14 4 M 0 8437 0 D 2033-02-13 Common Stock 8437 36563 D Consists of 25,561 shares of common stock and 79,919 restricted stock units ("RSUs"). The price reported in Column 4 is a weighted average price. The shares were sold in multiple transactions at prices ranging from $17.96 to $18.36. Full information regarding the number of shares sold at each separate price can be furnished to the SEC staff upon request. Consists of 899 shares of common stock and 79,919 RSUs. 36,563 shares remain unvested under this stock option. The first vesting event occurred on April 1, 2023 and the remainder will vest in fifteen quarterly installments thereafter; provided the reporting person continues to have a service relationship with the Issuer on such vesting date. /s/ Junlin Ho, Attorney-in-Fact for Mo Qatanani 2023-12-15