Document Format Files
| Seq | Description | Document | Type | Size |
|---|---|---|---|---|
| 1 | S-1 | a2235501zs-1.htm | S-1 | 2397933 |
| 2 | EX-3.1 | a2235501zex-3_1.htm | EX-3.1 | 177691 |
| 3 | EX-3.3 | a2235501zex-3_3.htm | EX-3.3 | 109565 |
| 4 | EX-4.1 | a2235501zex-4_1.htm | EX-4.1 | 308007 |
| 5 | EX-4.3 | a2235501zex-4_3.htm | EX-4.3 | 102043 |
| 6 | EX-10.1 | a2235501zex-10_1.htm | EX-10.1 | 443229 |
| 7 | EX-10.6 | a2235501zex-10_6.htm | EX-10.6 | 220654 |
| 8 | EX-10.7 | a2235501zex-10_7.htm | EX-10.7 | 125799 |
| 9 | EX-10.8 | a2235501zex-10_8.htm | EX-10.8 | 39792 |
| 10 | EX-10.9 | a2235501zex-10_9.htm | EX-10.9 | 166271 |
| 11 | EX-10.10 | a2235501zex-10_10.htm | EX-10.10 | 29635 |
| 12 | EX-10.11 | a2235501zex-10_11.htm | EX-10.11 | 25513 |
| 13 | EX-10.12 | a2235501zex-10_12.htm | EX-10.12 | 27931 |
| 14 | EX-10.13 | a2235501zex-10_13.htm | EX-10.13 | 829501 |
| 15 | EX-10.14 | a2235501zex-10_14.htm | EX-10.14 | 879920 |
| 16 | EX-21.1 | a2235501zex-21_1.htm | EX-21.1 | 2520 |
| 17 | EX-23.1 | a2235501zex-23_1.htm | EX-23.1 | 2640 |
| 18 | G360261.JPG | g360261.jpg | GRAPHIC | 24135 |
| 19 | G355971.JPG | g355971.jpg | GRAPHIC | 101900 |
| 20 | G667738.JPG | g667738.jpg | GRAPHIC | 100239 |
| 21 | G259062.JPG | g259062.jpg | GRAPHIC | 72116 |
| 22 | G411583.JPG | g411583.jpg | GRAPHIC | 24278 |
| 23 | G113513.JPG | g113513.jpg | GRAPHIC | 75859 |
| 24 | G713293.JPG | g713293.jpg | GRAPHIC | 29423 |
| 25 | G486143.JPG | g486143.jpg | GRAPHIC | 70365 |
| 26 | G275515.JPG | g275515.jpg | GRAPHIC | 55148 |
| 27 | G54179.JPG | g54179.jpg | GRAPHIC | 38676 |
| 28 | G755194.JPG | g755194.jpg | GRAPHIC | 22425 |
| 29 | G116785.JPG | g116785.jpg | GRAPHIC | 112143 |
| 30 | G593080.JPG | g593080.jpg | GRAPHIC | 34961 |
| 31 | G85522LOI001.JPG | g85522loi001.jpg | GRAPHIC | 2398 |
| 32 | G85522LW01I001.JPG | g85522lw01i001.jpg | GRAPHIC | 5062 |
| 33 | G85522LYI001.GIF | g85522lyi001.gif | GRAPHIC | 316344 |
| 34 | G85522LYI002.GIF | g85522lyi002.gif | GRAPHIC | 362411 |
| 35 | G85522LYI003.GIF | g85522lyi003.gif | GRAPHIC | 362064 |
| 36 | G85522LYI004.GIF | g85522lyi004.gif | GRAPHIC | 322034 |
| 37 | G85522LYI005.GIF | g85522lyi005.gif | GRAPHIC | 34247 |
| 38 | G85522LYI006.GIF | g85522lyi006.gif | GRAPHIC | 140840 |
| 39 | G85522LYI007.GIF | g85522lyi007.gif | GRAPHIC | 29841 |
| 40 | G85522NAI001.GIF | g85522nai001.gif | GRAPHIC | 338411 |
| 41 | G85522NAI002.GIF | g85522nai002.gif | GRAPHIC | 368146 |
| 42 | G85522NAI003.GIF | g85522nai003.gif | GRAPHIC | 310974 |
| 43 | G85522NAI004.GIF | g85522nai004.gif | GRAPHIC | 54479 |
| 44 | G85522NAI005.GIF | g85522nai005.gif | GRAPHIC | 95827 |
| 45 | G85522NCI001.GIF | g85522nci001.gif | GRAPHIC | 466349 |
| 46 | G85522NCI002.GIF | g85522nci002.gif | GRAPHIC | 528345 |
| 47 | G85522NCI003.GIF | g85522nci003.gif | GRAPHIC | 524991 |
| 48 | G85522NCI004.GIF | g85522nci004.gif | GRAPHIC | 478991 |
| 49 | G85522NCI005.GIF | g85522nci005.gif | GRAPHIC | 46561 |
| 50 | G85522NCI006.GIF | g85522nci006.gif | GRAPHIC | 56980 |
| 51 | G85522IS21I001.JPG | g85522is21i001.jpg | GRAPHIC | 98314 |
| Complete submission text file | 0001047469-18-003300.txt | 13749445 |
IRS No.: 823750435 | State of Incorp.: DE | Fiscal Year End: 1231
Type: S-1 | Act: 33 | File No.: 333-224493 | Film No.: 18784546
SIC: 2836 Biological Products, (No Diagnostic Substances)
Office of Life Sciences
