X0306 4 2019-01-31 0 0001103021 BIODELIVERY SCIENCES INTERNATIONAL INC BDSI 0001726687 Plesha Scott M. C/O BIODELIVERY SCIENCES INTL, INC., 4131 PARKLAKE AVE. SUITE 225 RALEIGH NC 27612 0 1 0 0 See Remarks Restricted Stock Units 0.00 2019-01-31 4 A 0 40000 0.00 A 2022-01-31 Common Stock 40000 40000 D Stock Options (Right to Buy) 3.90 2019-01-31 4 A 0 245000 0.00 A 2029-01-31 Common Stock 245000 245000 D The Restricted Stock Units ("RSUs") were issued to the Reporting Person on January 31, 2019, pursuant to a grant under the Issuer's 2011 Equity Incentive Plan, as amended (the "Plan"). The award is subject to time-based vesting and will vest in equal portions on: (i) January 31, 2020; (ii) January 31, 2021; and (iii) January 31, 2022. Upon vesting, each RSU entitles the Reporting Person to one share of the Issuer's common stock. The Reporting Person has been granted the right to elect to defer actual payment of a vested RSU award, subject to compliance with Internal Revenue Code Section 409A. The exercise price of the stock options issued to the Reporting Person is the volume-weighted average price of the Company's common stock for the 30-day period ending on January 30, 2019. The stock options were issued to the Reporting Person on January 31, 2019, pursuant to a grant under the Plan. The award is subject to time-based vesting and will vest in equal portions on: (i) January 31, 2020; (ii) January 31, 2021; and (iii) January 31, 2022. President and Chief Commercial Officer /s/ Scott Plesha 2019-02-04