Fair Value Measurements and Fair Value of Financial Instruments - Unrealized Gain (Loss) (Details) - USD ($) $ in Thousands	Mar. 31, 2023	Dec. 31, 2022
Fair Value Measurement Inputs and Valuation Techniques [Line Items]
Amortized Cost Basis	$ 410,605	$ 427,647
Unrealized Gains	292	40
Unrealized Losses	(387)	(1,291)
Fair Value	410,510	426,396
Total cash equivalents
Fair Value Measurement Inputs and Valuation Techniques [Line Items]
Amortized Cost Basis	48,385	53,208
Unrealized Gains	1	0
Unrealized Losses	0	0
Fair Value	48,386	53,208
Total cash equivalents | Money market funds
Fair Value Measurement Inputs and Valuation Techniques [Line Items]
Amortized Cost Basis	41,906	53,208
Unrealized Gains	0	0
Unrealized Losses	0	0
Fair Value	41,906	53,208
Total cash equivalents | U.S. Treasury securities
Fair Value Measurement Inputs and Valuation Techniques [Line Items]
Amortized Cost Basis	6,479
Unrealized Gains	1
Unrealized Losses	0
Fair Value	6,480
Total investments
Fair Value Measurement Inputs and Valuation Techniques [Line Items]
Amortized Cost Basis	362,220	374,439
Unrealized Gains	291	40
Unrealized Losses	(387)	(1,291)
Fair Value	362,124	373,188
Total investments | U.S. Treasury securities
Fair Value Measurement Inputs and Valuation Techniques [Line Items]
Amortized Cost Basis	223,488	228,563
Unrealized Gains	258	25
Unrealized Losses	(152)	(896)
Fair Value	223,594	227,692
Total investments | U.S. Non-Treasury securities
Fair Value Measurement Inputs and Valuation Techniques [Line Items]
Amortized Cost Basis	16,818	10,699
Unrealized Gains	24	6
Unrealized Losses	(1)	(3)
Fair Value	16,841	10,702
Total investments | Commercial paper
Fair Value Measurement Inputs and Valuation Techniques [Line Items]
Amortized Cost Basis	58,372	55,561
Unrealized Gains	2	3
Unrealized Losses	(74)	(131)
Fair Value	58,300	55,433
Total investments | Corporate debt securities
Fair Value Measurement Inputs and Valuation Techniques [Line Items]
Amortized Cost Basis	63,542	79,616
Unrealized Gains	7	6
Unrealized Losses	(160)	(261)
Fair Value	$ 63,389	$ 79,361