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Consolidated Statements of Cash Flows - USD ($)
$ in Thousands
12 Months Ended
Dec. 31, 2022
Dec. 31, 2021
OPERATING ACTIVITIES    
Net loss $ (92,966) $ (71,169)
Adjustments to reconcile net loss to net cash used in operating activities:    
Stock-based compensation 33,673 25,927
Depreciation and amortization 3,942 2,558
Loss on disposal of property and equipment 332 0
Net amortization of premium on available-for-sale securities (833) 1,197
Provision for inventory excess and obsolescence 507 0
Non-cash operating lease expense 1,959 1,005
Changes in operating assets and liabilities:    
Accounts receivable, net (1,820) (2,495)
Related party receivables (521) (1,184)
Other receivables (533) (203)
Prepaid expenses and other current assets (727) (2,884)
Inventory (1,590) (3,594)
Other assets (354) (94)
Accounts payable (1,553) 1,603
Deferred revenue (243) 126
Deferred rent 0 0
Accrued expenses 40 2,277
Accrued research and development 0 627
Operating lease liabilities (304) 91
Other current liabilities 207 0
Other noncurrent liabilities 4 (135)
Net cash used in operating activities (60,780) (46,347)
INVESTING ACTIVITIES    
Purchases of property and equipment (10,265) (6,922)
Proceeds from disposal of property and equipment 170 0
Purchase of available-for-sale securities (366,268) (279,956)
Proceeds from maturities of available-for-sale securities 253,645 116,000
Net cash used in investing activities (122,718) (170,878)
FINANCING ACTIVITIES    
Proceeds from issuance of common stock upon follow-on public offering, net of issuance costs 0 102,959
Proceeds from return of profit 0 11,403
Repurchase of Class A common stock (20) (35)
Proceeds from exercise of Class A common stock options including early exercised options 3,138 1,885
Proceeds from issuance of common stock in connection with employee stock purchase plan 775 422
Net cash provided by financing activities 3,893 116,634
Net decrease in cash, cash equivalents and restricted cash (179,605) (100,591)
Cash, cash equivalents and restricted cash, beginning of period 233,337 333,928
Cash, cash equivalents and restricted cash, end of period 53,732 233,337
SUPPLEMENTAL DISCLOSURE OF CASH FLOW INFORMATION    
Cash paid for income taxes 232 645
SUPPLEMENTAL DISCLOSURE OF NON-CASH ACTIVITIES    
Property, Plant and Equipment, Transfers and Changes 928 0
Lease liability obtained in exchange for right-of-use assets 6,855 23,232
Accounts Payable    
SUPPLEMENTAL DISCLOSURE OF NON-CASH ACTIVITIES    
Property and equipment purchases 54 186
Accrued Liabilities    
SUPPLEMENTAL DISCLOSURE OF NON-CASH ACTIVITIES    
Property and equipment purchases $ 300 $ 269