Fair Value Measurements and Fair Value of Financial Instruments - Assets Measured on Recurring Basis (Details) - Fair Value, Recurring - USD ($) $ in Thousands	Dec. 31, 2022	Dec. 31, 2021
Fair Value Measurement Inputs and Valuation Techniques [Line Items]
Total cash equivalents	$ 53,208	$ 232,813
Investments, Fair Value Disclosure	373,188	260,447
Total assets measured at fair value	426,396	493,260
U.S. Treasury securities
Fair Value Measurement Inputs and Valuation Techniques [Line Items]
Investments, Fair Value Disclosure	227,692	260,447
U.S. Non-Treasury securities
Fair Value Measurement Inputs and Valuation Techniques [Line Items]
Investments, Fair Value Disclosure	10,702
Commercial paper
Fair Value Measurement Inputs and Valuation Techniques [Line Items]
Investments, Fair Value Disclosure	55,433
Corporate debt securities
Fair Value Measurement Inputs and Valuation Techniques [Line Items]
Investments, Fair Value Disclosure	79,361
Money market funds
Fair Value Measurement Inputs and Valuation Techniques [Line Items]
Total cash equivalents		232,813
Level 1
Fair Value Measurement Inputs and Valuation Techniques [Line Items]
Total cash equivalents	53,208	232,813
Investments, Fair Value Disclosure	0	0
Total assets measured at fair value	53,208	232,813
Level 1 | U.S. Treasury securities
Fair Value Measurement Inputs and Valuation Techniques [Line Items]
Investments, Fair Value Disclosure	0	0
Level 1 | U.S. Non-Treasury securities
Fair Value Measurement Inputs and Valuation Techniques [Line Items]
Investments, Fair Value Disclosure	0
Level 1 | Commercial paper
Fair Value Measurement Inputs and Valuation Techniques [Line Items]
Investments, Fair Value Disclosure	0
Level 1 | Corporate debt securities
Fair Value Measurement Inputs and Valuation Techniques [Line Items]
Investments, Fair Value Disclosure	0
Level 1 | Money market funds
Fair Value Measurement Inputs and Valuation Techniques [Line Items]
Total cash equivalents		232,813
Level 2
Fair Value Measurement Inputs and Valuation Techniques [Line Items]
Total cash equivalents	0	0
Investments, Fair Value Disclosure	373,188	260,447
Total assets measured at fair value	373,188	260,447
Level 2 | U.S. Treasury securities
Fair Value Measurement Inputs and Valuation Techniques [Line Items]
Investments, Fair Value Disclosure	227,692	260,447
Level 2 | U.S. Non-Treasury securities
Fair Value Measurement Inputs and Valuation Techniques [Line Items]
Investments, Fair Value Disclosure	10,702
Level 2 | Commercial paper
Fair Value Measurement Inputs and Valuation Techniques [Line Items]
Investments, Fair Value Disclosure	55,433
Level 2 | Corporate debt securities
Fair Value Measurement Inputs and Valuation Techniques [Line Items]
Investments, Fair Value Disclosure	79,361
Level 2 | Money market funds
Fair Value Measurement Inputs and Valuation Techniques [Line Items]
Total cash equivalents		0
Level 3
Fair Value Measurement Inputs and Valuation Techniques [Line Items]
Total cash equivalents	0	0
Investments, Fair Value Disclosure	0	0
Total assets measured at fair value	0	0
Level 3 | U.S. Treasury securities
Fair Value Measurement Inputs and Valuation Techniques [Line Items]
Investments, Fair Value Disclosure	0	0
Level 3 | U.S. Non-Treasury securities
Fair Value Measurement Inputs and Valuation Techniques [Line Items]
Investments, Fair Value Disclosure	0
Level 3 | Commercial paper
Fair Value Measurement Inputs and Valuation Techniques [Line Items]
Investments, Fair Value Disclosure	0
Level 3 | Corporate debt securities
Fair Value Measurement Inputs and Valuation Techniques [Line Items]
Investments, Fair Value Disclosure	$ 0
Level 3 | Money market funds
Fair Value Measurement Inputs and Valuation Techniques [Line Items]
Total cash equivalents		$ 0