Fair Value Measurements and Fair Value of Financial Instruments - Unrealized Gain (Loss) (Details) - USD ($) $ in Thousands	Sep. 30, 2022	Dec. 31, 2021
Fair Value Measurement Inputs and Valuation Techniques [Line Items]
Amortized Cost Basis	$ 443,629	$ 493,796
Unrealized Gains	10	0
Unrealized Losses	(2,702)	(536)
Fair Value	440,937	493,260
Money market funds
Fair Value Measurement Inputs and Valuation Techniques [Line Items]
Amortized Cost Basis		232,813
Unrealized Gains		0
Unrealized Losses		0
Fair Value		232,813
Money market funds | Total cash equivalents
Fair Value Measurement Inputs and Valuation Techniques [Line Items]
Amortized Cost Basis	55,155
Unrealized Gains	0
Unrealized Losses	0
Fair Value	55,155
U.S. Treasury securities
Fair Value Measurement Inputs and Valuation Techniques [Line Items]
Amortized Cost Basis		260,983
Unrealized Gains		0
Unrealized Losses		(536)
Fair Value		260,447
U.S. Treasury securities | Total investments
Fair Value Measurement Inputs and Valuation Techniques [Line Items]
Amortized Cost Basis	239,702
Unrealized Gains	3
Unrealized Losses	(2,134)
Fair Value	237,571
Commercial paper | Total cash equivalents
Fair Value Measurement Inputs and Valuation Techniques [Line Items]
Amortized Cost Basis	3,979
Unrealized Gains	0
Unrealized Losses	(3)
Fair Value	3,976
Commercial paper | Total investments
Fair Value Measurement Inputs and Valuation Techniques [Line Items]
Amortized Cost Basis	61,727
Unrealized Gains	0
Unrealized Losses	(142)
Fair Value	61,585
Corporate debt securities | Total cash equivalents
Fair Value Measurement Inputs and Valuation Techniques [Line Items]
Amortized Cost Basis	8,937
Unrealized Gains	1
Unrealized Losses	0
Fair Value	8,938
Corporate debt securities | Total investments
Fair Value Measurement Inputs and Valuation Techniques [Line Items]
Amortized Cost Basis	74,129
Unrealized Gains	6
Unrealized Losses	(423)
Fair Value	73,712
Total cash equivalents
Fair Value Measurement Inputs and Valuation Techniques [Line Items]
Amortized Cost Basis		232,813
Unrealized Gains		0
Unrealized Losses		0
Fair Value		232,813
Total cash equivalents | Total cash equivalents
Fair Value Measurement Inputs and Valuation Techniques [Line Items]
Amortized Cost Basis	68,071
Unrealized Gains	1
Unrealized Losses	(3)
Fair Value	68,069
Total investments
Fair Value Measurement Inputs and Valuation Techniques [Line Items]
Amortized Cost Basis		260,983
Unrealized Gains		0
Unrealized Losses		(536)
Fair Value		$ 260,447
Total investments | Total investments
Fair Value Measurement Inputs and Valuation Techniques [Line Items]
Amortized Cost Basis	375,558
Unrealized Gains	9
Unrealized Losses	(2,699)
Fair Value	$ 372,868