Income Taxes - Schedule of Income Tax Expense (Details) - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2021	Dec. 31, 2020
Income Tax Disclosure [Abstract]
Federal tax benefits at statutory rate	$ (14,887)	$ (6,859)
State taxes, net of federal benefit	(1,275)	(1,065)
Change in valuation allowance	17,751	6,248
Stock-based compensation tax deduction over book expense	(2,790)	0
Permanent differences	(47)	557
Gain on PrognomIQ transaction	0	1,392
Research and development credits	(1,697)	(104)
Executive compensation limitations	2,806	0
Other	139	(169)
Total income tax expense	$ 0	$ 0