Equity Incentive Plans - Activity of Stock Options for the Period (Details) - USD ($) $ / shares in Units, $ in Thousands	12 Months Ended
	Dec. 31, 2021	Dec. 31, 2020
Options Outstanding
Beginning balance (in shares)	9,551,105
Options granted (in shares)	1,678,042
Options exercised (in shares)	(1,040,515)
Options cancelled and forfeited (in shares)	(355,708)
Ending balance (in shares)	9,832,924	9,551,105
Vested and exercisable (in shares)	3,062,451
Weighted-Average Exercise Price
Beginning balance (in dollars per share)	$ 5.55
Options granted (in usd per share)	46.89
Options exercised (in usd per share)	1.84
Options cancelled and forfeited (in usd per share)	19.64
Ending balance (in dollars per share)	12.49	$ 5.55
Vested and exercisable (in usd per share)	$ 5.32
Options outstanding, Weighted Average Remaining Term (Years)	8 years 5 months 23 days	8 years 11 months 26 days
Options vested and exercisable, Weighted Average Remaining Term (Years)	8 years 10 days
Options outstanding, Aggregate Intrinsic Value	$ 139,143	$ 483,194
Options vested and exercisable, Aggregate Intrinsic Value	$ 55,309