X0407 4 2023-04-03 0 0001704292 Zai Lab Ltd ZLAB 0001725189 Smiley Joshua L C/O ZAI LAB LIMITED 314 MAIN STREET, 4TH FLOOR, SUITE 100 CAMBRIDGE MA 02142 0 1 0 0 See Remarks 0 Stock Options (Right to Buy) 33.95 2023-04-03 4 A 0 150050 0.00 A 2033-04-03 American Depositary Shares 150050 150050 D Restricted Share Units 2023-04-03 4 A 0 28580 0.00 A American Depositary Shares 28580 28580 D The Stock Options are exercisable for American Depositary Shares (ADSs). The number of securities underlying each option and the exercise price therefor are represented in ADSs. Each ADS represents ten Ordinary Shares of the issuer. The Stock Options vest in equal annual installments over four years beginning on 04/03/2024, the first anniversary of the date of grant. Each ADS represents ten Ordinary Shares of the issuer. Each Restricted Share Unit represents a contingent right to receive one American Depositary Share (ADS), which represents ten Ordinary Shares of the issuer. The Restricted Share Units vest in equal annual installments over four years beginning on 04/03/2024, the first anniversary of the date of grant. Vested shares will be delivered to the reporting person following vesting. President and Chief Operating Officer /s/ Bruce Blefeld, Attorney-in-Fact 2023-04-05