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Members’ Equity (Tables)
9 Months Ended
Sep. 30, 2021
Equity [Abstract]  
Schedule of Share-based Compensation Expense
Total share-based compensation expense related to share based awards was comprised of the following (in thousands):
 Three Months Ended
September 30,
Nine Months Ended
September 30,
2021202020212020
Research and development expense$3,697 $2,180 $10,746 $4,606 
General and administrative expense3,959 5,069 16,520 10,653 
Total share-based compensation expense$7,656 $7,249 $27,266 $15,259 
Share-based compensation expense by type of share-based award (in thousands):
Three Months Ended
September 30,
Nine Months Ended
September 30,
2021202020212020
Profit Interest Award Units$— $— $— $329 
Stock Options5,596 2,212 14,267 3,814 
Employee Stock Purchase Plan103 — 213 — 
RSAs and RSUs1,957 5,037 12,786 11,116 
$7,656 $7,249 $27,266 $15,259 
Schedule of Valuation Assumptions
The fair value of the profits interest awards is estimated using an option pricing model with the following assumptions:
Nine Months Ended
September 30,
2020
Members’ equity value (in thousands)$271,207 
Threshold amounts (in thousands)$309,824 
Risk free interest rate1.5 %
Volatility75.0 %
Time to liquidity (in years)1.1
Lack of marketability discount26.5 %
Grant date fair value$3.06 
The fair value of the stock options granted during the nine months ended September 30, 2021 and September 30, 2020 was determined with the following assumptions:
September 30, 2021September 30, 2020
Expected volatility
73.9% - 76.6%
76.6% - 78.2%
Average expected term (in years)
5.2 - 6.2
5.7 - 6.0
Risk-free interest rate
0.5% - 1.1%
0.4% - 0.5%
Expected dividend yield— %— %
Schedule of Valuation Assumptions, ESPP
The weighted average assumptions used to estimate the fair value of stock purchase rights under the employee stock purchase plan (“ESPP”) are as follows:
Ended September 30,
20212020
ESPP
Volatility64 %— 
Expected term (years)0.5— 
Risk free rate— %— 
Expected dividend yield— — 
Share-based Compensation Expense by Type of Share-based Award
Total unrecognized estimated compensation cost by type of award and the weighted average requisite service period over which such expense is expected to be recognized (in thousands, unless otherwise noted):

September 30, 2021
Unrecognized
Expense
Remaining
Weighted-Average Recognition Period
(years)
Stock options$65,008 3.05
RSAs$1,472 1.84
RSUs$7,793 2.29
ESPP$— 0