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Convertible Preferred Stock and Stockholders' Equity (Tables)
9 Months Ended
Sep. 30, 2022
Summary of Stock Option Activities

A summary of the Company’s stock option activities during the nine months ended September 30, 2022 is as follows:

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Weighted-

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Weighted-

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Average

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Average

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Aggregate

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Exercise

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Remaining

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Intrinsic

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Price Per

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Contract Term

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Value

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Total Options

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Share

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(in years)

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(in millions)

Outstanding as of December 31, 2021

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1,734,696

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$

8.50

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8.8

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$

7.6

Granted

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1,170,928

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$

8.04

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​

​

​

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Exercised

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(31,152)

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$

4.26

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​

​

​

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Forfeited or cancelled

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(244,214)

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$

10.39

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​

​

​

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Outstanding as of September 30, 2022

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2,630,258

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$

8.17

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8.6

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$

1.4

Vested and expected to vest as of September 30, 2022

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2,630,258

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$

8.17

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8.6

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$

1.4

Vested and exercisable as of September 30, 2022

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905,005

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$

6.51

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7.7

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$

0.8

Summary of Stock-Based Compensation Expense Recognized

The Company recognized stock-based compensation expense as follows (in thousands):

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Three Months Ended
September 30,

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Nine Months Ended
September 30,

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        2022        

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        2021        

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        2022        

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        2021        

Research and development

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$

728

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$

683

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$

2,821

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$

1,452

General and administrative

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​

204

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​

179

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​

770

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​

368

Total stock-based compensation expense

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$

932

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$

862

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$

3,591

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$

1,820

Weighted-Average Assumptions Used in Black-Scholes Option Pricing Model to Determine Fair Value of Stock Option Grants

The weighted-average assumptions used in the Black-Scholes option pricing model to determine the fair value of the stock option grants were as follows:

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Three Months Ended
September 30,

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Nine Months Ended
September 30,

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        2022        

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        2021        

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        2022        

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        2021        

Risk-free interest rate

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3.24%

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0.90%

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1.60% - 3.24%

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0.80% - 1.12%

Expected volatility

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103.3%

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115.5%

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88.1% - 112.1%

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115.3% -118.7%

Expected term (in years)

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6.1

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6.1

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5.3 - 6.1

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5.0 - 6.1

Expected dividend yield

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0%

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0%

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0%

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0%

Schedule of Common Stock Reserved for Future Issuance

Common stock reserved for future issuance consist of the following:

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September 30,
2022

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December 31,
2021

Stock options

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2,630,258

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1,734,696

Restricted stock units

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9,289

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—

Reserved for future equity award grants

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3,056,959

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2,933,930

Reserved for future ESPP issuances

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466,585

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259,689

Total

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6,163,091

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4,928,315

Restricted Stock Units (RSU)  
Summary of Restricted Stock Units Activities

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Weighted-

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Aggregate

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Total

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Average

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Intrinsic

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Restricted

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Grant Date

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Value

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Stock Units

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Fair Values

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(in millions)

Outstanding as of December 31, 2021

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—

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$

—

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$

—

Granted

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9,289

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$

6.25

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​

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Vested

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—

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$

—

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​

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Forfeited or cancelled

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—

​

$

—

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​

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Outstanding as of September 30, 2022

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9,289

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$

6.25

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$

—

Employee Stock Purchase Plan  
Weighted-Average Assumptions Used in Black-Scholes Option Pricing Model to Determine Fair Value of Stock Option Grants

The weighted average assumptions used in the Black-Scholes option pricing model to estimate the fair value of purchase rights granted under the ESPP were as follows:

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Nine Months Ended
September 30,

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2022

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        2021        

Risk-free interest rate

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0.1%

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0.1%

Expected volatility

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143.2%

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127.8%

Expected term (in years)

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1.9

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1.4

Expected dividend yield

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0%

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0%