144 0001422996 XXXXXXXX LIVE 0001724521 Arcus Biosciences, Inc. 001-38419 3928 Point Eden Way Hayward CA 94545 1-510-694-6200 Juan Jaen Officer Class A Common Stock Goldman Sachs & Co. LLC 200 West Street New York NY 10282 50000 1440000 125773162 06/24/2026 NYSE Class A Common Stock 06/15/2022 Acquired as compensation -- Restricted Stock Units The Issuer N 3865 06/15/2022 Compensation Class A Common Stock 06/15/2023 Acquired as compensation -- Restricted Stock Units The Issuer N 8930 06/15/2023 Compensation Class A Common Stock 12/07/2023 Acquired as compensation -- Restricted Stock Units The Issuer N 937 12/07/2023 Compensation Class A Common Stock 12/11/2023 Acquired as compensation -- Restricted Stock Units The Issuer N 1148 12/11/2023 Compensation Class A Common Stock 12/11/2023 Acquired as compensation -- Restricted Stock Units The Issuer N 3798 12/11/2023 Compensation Class A Common Stock 12/11/2023 Acquired as compensation -- Restricted Stock Units The Issuer N 4015 12/11/2023 Compensation Class A Common Stock 12/11/2023 Acquired as compensation -- Restricted Stock Units The Issuer N 1552 12/11/2023 Compensation Class A Common Stock 12/15/2023 Acquired as compensation -- Restricted Stock Units The Issuer N 270 12/15/2023 Compensation Class A Common Stock 06/15/2024 Acquired as compensation -- Restricted Stock Units The Issuer N 6781 06/15/2024 Compensation Class A Common Stock 06/15/2024 Acquired as compensation -- Restricted Stock Units The Issuer N 2388 06/15/2024 Compensation Class A Common Stock 12/15/2024 Acquired as compensation -- Restricted Stock Units The Issuer N 3852 12/15/2024 Compensation Class A Common Stock 12/15/2024 Acquired as compensation -- Restricted Stock Units The Issuer N 5647 12/15/2024 Compensation Class A Common Stock 12/15/2024 Acquired as compensation -- Restricted Stock Units The Issuer N 4932 12/15/2024 Compensation Class A Common Stock 11/03/2017 Acquired as compensation -- Restricted Stock Units The Issuer N 1885 11/03/2017 Compensation N The Juan Carlos Jaen and Anita Galeana 2000 Trust 3928 Point Eden Way Hayward CA 94545 Class A Common Stock 06/22/2026 9236 249661.09 The Juan Carlos Jaen and Anita Galeana 2000 Trust 3928 Point Eden Way Hayward CA 94545 Class A Common Stock 06/23/2026 15764 437099.46 The sales of shares set forth herein are made in connection with a selling plan dated 02/27/2026, that is intended to comply with Rule 10b5-1(c). All shares to be sold by the Juan Carlos Jaen and Anita Galeana 2000 Trust. 06/24/2026 02/27/2026 Goldman Sachs & Co. LLC on behalf of Juan Jaen