144 0001422996 XXXXXXXX LIVE 0001724521 Arcus Biosciences, Inc. 001-38419 3928 Point Eden Way Hayward CA 94545 1-510-694-6200 Juan Jaen Officer Class A Common Stock Goldman Sachs & Co. LLC 200 West Street New York NY 10282 25000 680750 125773162 06/22/2026 NYSE Class A Common Stock 12/15/2021 Acquired as compensation -- Restricted Stock Units The Issuer N 2871 12/15/2021 Compensation Class A Common Stock 12/15/2022 Acquired as compensation -- Restricted Stock Units The Issuer N 3146 12/15/2022 Compensation Class A Common Stock 12/15/2022 Acquired as compensation -- Restricted Stock Units The Issuer N 5075 12/15/2022 Compensation Class A Common Stock 06/15/2021 Acquired as compensation -- Restricted Stock Units The Issuer N 8893 06/15/2021 Compensation Class A Common Stock 06/15/2022 Acquired as compensation -- Restricted Stock Units The Issuer N 5015 06/15/2022 Compensation Y The sales of shares set forth herein are made in connection with a selling plan dated 02/27/2026, that is intended to comply with Rule 10b5-1(c). All shares to be sold by the Juan Carlos Jaen and Anita Galeana 2000 Trust. 06/22/2026 02/27/2026 Goldman Sachs & Co. LLC on behalf of Juan Jaen