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License and Collaborations - Additional Information (Details) - USD ($)
3 Months Ended 12 Months Ended
Mar. 31, 2026
Dec. 31, 2025
Dec. 31, 2025
Dec. 31, 2024
Dec. 31, 2023
Dec. 31, 2020
Dec. 31, 2017
License and Collaboration Agreements [Line Items]              
Total revenues     $ 33,000,000 $ 51,000,000 $ 37,000,000    
Receivable from collaboration partners, current   $ 11,000,000 11,000,000 20,000,000      
Other current liabilities   154,000,000 154,000,000 123,000,000      
Other noncurrent liabilities   135,000,000 135,000,000 157,000,000      
Taiho Collaboration Agreement              
License and Collaboration Agreements [Line Items]              
Milestone payments     19,000,000        
Milestone payments, received     12,000,000        
Receivable from collaboration partners, current   10,000,000 10,000,000 14,000,000      
Other liabilities   44,000,000 44,000,000        
Taiho Collaboration Agreement | Forecast              
License and Collaboration Agreements [Line Items]              
Milestone payments, received $ 7,000,000            
AstraZeneca Agreement              
License and Collaboration Agreements [Line Items]              
Milestone payments           $ 24,000,000  
Development cost recorded within research and development expenses     20,000,000 14,000,000 6,000,000    
Other current liabilities   12,000,000 12,000,000        
Other noncurrent liabilities       26,000,000      
Taiho Pharmaceutical Co., Ltd | Taiho Agreement              
License and Collaboration Agreements [Line Items]              
Option period             5 years
Non refundable and non creditable cash payments             $ 35,000,000
Payment for option exercise   15,000,000   15,000,000      
Royalties payable term             10 years
Payment for option exercise   15,000,000          
Total revenues     7,000,000 15,000,000 5,000,000    
Reimbursement of research and development expense     34,000,000 28,000,000 8,000,000    
Taiho Pharmaceutical Co., Ltd | Taiho Agreement | Minimum              
License and Collaboration Agreements [Line Items]              
Payment for option exercise             $ 3,000,000
Taiho Pharmaceutical Co., Ltd | Taiho Agreement | Maximum              
License and Collaboration Agreements [Line Items]              
Payment for option exercise             15,000,000
Additional clinical and regulatory milestone payments receivable   172,000,000         130,000,000
Contingent milestone payments receivable   $ 145,000,000 145,000,000       $ 145,000,000
STAR-221 Development Activities | Taiho Collaboration Agreement              
License and Collaboration Agreements [Line Items]              
Milestone payments         28,000,000    
STAR-121 Development Activities | Taiho Collaboration Agreement              
License and Collaboration Agreements [Line Items]              
Milestone payments       26,000,000      
Milestone payments, received     10,000,000 16,000,000      
WuXi Biologics License Agreement | anti-PD-1              
License and Collaboration Agreements [Line Items]              
Milestone payments     0 0 0    
Royalty expense     0 0 0    
WuXi Biologics License Agreement | anti-CD39              
License and Collaboration Agreements [Line Items]              
Milestone payments     0 0      
Royalty expense     0 0      
WuXi Biologics License Agreement | anti-CD39 | Research and Development              
License and Collaboration Agreements [Line Items]              
Milestone payments         1,000,000    
WuXi Biologics License Agreement | Maximum | anti-PD-1              
License and Collaboration Agreements [Line Items]              
Clinical regulatory milestone payments     50,000,000        
Clinical, regulatory and commercialization milestone payments     375,000,000        
WuXi Biologics License Agreement | Maximum | anti-CD39              
License and Collaboration Agreements [Line Items]              
Additional clinical, regulatory and commercialization milestone payments     14,000,000        
Abmuno License Agreement              
License and Collaboration Agreements [Line Items]              
Milestone payments     0 0 0    
Royalty expense     0 $ 0 $ 0    
Additional clinical, regulatory and commercialization milestone payments     $ 88,000,000