XML 55 R38.htm IDEA: XBRL DOCUMENT v3.25.3
License and Collaborations (Details) - USD ($)
$ in Millions
1 Months Ended 3 Months Ended 9 Months Ended 12 Months Ended
Oct. 31, 2025
Mar. 31, 2026
Dec. 31, 2025
Sep. 30, 2025
Mar. 31, 2025
Sep. 30, 2024
Mar. 31, 2024
Sep. 30, 2025
Sep. 30, 2024
Dec. 31, 2023
Dec. 31, 2020
Dec. 31, 2017
Dec. 31, 2024
License And Collaboration Agreements [Line Items]                          
Total revenues       $ 6   $ 7   $ 22 $ 28        
Receivable from collaboration partners, current       11       11         $ 20
Other noncurrent assets       65       65         73
Other current liabilities       141       141         123
Other noncurrent liabilities       152       152         157
Taiho Collaboration Agreement                          
License And Collaboration Agreements [Line Items]                          
Milestone payments           19              
Milestone payments, received         $ 12                
Receivable from collaboration partners, current       11       11         14
Other liabilities       42       42         36
Taiho Collaboration Agreement | Forecast                          
License And Collaboration Agreements [Line Items]                          
Milestone payments, received   $ 7                      
AstraZeneca Agreement                          
License And Collaboration Agreements [Line Items]                          
Milestone payments                     $ 24    
Development cost recorded within research and development expenses       7   4   16 10        
Other current liabilities       28       28          
Other noncurrent liabilities                         $ 26
Gilead Collaboration Agreement                          
License And Collaboration Agreements [Line Items]                          
Other noncurrent assets                   $ 6      
Development cost recorded within research and development expenses                 6        
Taiho Pharmaceutical Co., Ltd | Taiho Agreement                          
License And Collaboration Agreements [Line Items]                          
Option period                       5 years  
Non refundable and non creditable cash payments                       $ 35  
Payment for option exercise           15              
Royalties payable term                       10 years  
Reimbursement of research and development expense       7   3   24 10        
Total revenues           18     25        
Taiho Pharmaceutical Co., Ltd | Taiho Agreement | Forecast                          
License And Collaboration Agreements [Line Items]                          
Payment for option exercise     $ 15                    
Taiho Pharmaceutical Co., Ltd | Taiho Agreement | Minimum                          
License And Collaboration Agreements [Line Items]                          
Payment for option exercise                       $ 3  
Taiho Pharmaceutical Co., Ltd | Taiho Agreement | Maximum                          
License And Collaboration Agreements [Line Items]                          
Payment for option exercise                       15  
Additional clinical and regulatory milestone payments receivable                       130  
Contingent milestone payments receivable                       $ 145  
Taiho Pharmaceutical Co., Ltd | Taiho Agreement | Maximum | Subsequent Event                          
License And Collaboration Agreements [Line Items]                          
Additional clinical and regulatory milestone payments receivable $ 172                        
Contingent milestone payments receivable $ 145                        
STAR-221 Development Activities | Taiho Collaboration Agreement                          
License And Collaboration Agreements [Line Items]                          
Milestone payments                   $ 28      
STAR-121 Development Activities | Taiho Collaboration Agreement                          
License And Collaboration Agreements [Line Items]                          
Milestone payments             $ 26            
Milestone payments, received         $ 10   $ 16            
WuXi Biologics License Agreement | anti-PD-1                          
License And Collaboration Agreements [Line Items]                          
Development milestone expense       0   0   0 0        
WuXi Biologics License Agreement | anti-CD39                          
License And Collaboration Agreements [Line Items]                          
Development milestone expense       0   0   0 0        
WuXi Biologics License Agreement | Maximum | anti-PD-1                          
License And Collaboration Agreements [Line Items]                          
Clinical regulatory milestone payments               50          
Clinical, regulatory and commercialization milestone payments               375          
WuXi Biologics License Agreement | Maximum | anti-CD39                          
License And Collaboration Agreements [Line Items]                          
Additional clinical, regulatory and commercialization milestone payments               14          
Abmuno License Agreement                          
License And Collaboration Agreements [Line Items]                          
Development milestone expense       $ 0   $ 0   0 $ 0        
Additional clinical, regulatory and commercialization milestone payments               $ 88