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License and Collaborations - Additional Information (Details) - USD ($)
$ in Millions
1 Months Ended 3 Months Ended 9 Months Ended 12 Months Ended
Oct. 31, 2024
Jul. 31, 2024
Jan. 31, 2024
Mar. 31, 2025
Sep. 30, 2024
Sep. 30, 2023
Sep. 30, 2024
Sep. 30, 2023
Dec. 31, 2020
Dec. 31, 2017
Dec. 31, 2023
License And Collaboration Agreements [Line Items]                      
Revenue recognized from amounts in deferred revenue at the beginning of the period         $ 33 $ 28 $ 212 $ 79      
Total revenues         48 32 232 86      
Receivable from collaboration partners, current         16   16       $ 38
Other noncurrent assets         75   75       106
Other current liabilities         97   97       76
Other noncurrent liabilities         136   136       142
Research and development expense         123 82 347 247      
Taiho Collaboration Agreement                      
License And Collaboration Agreements [Line Items]                      
Total revenues         3 4 10 4      
Receivable from collaboration partners, current         14   14       18
Taiho Collaboration Agreement | Subsequent Event                      
License And Collaboration Agreements [Line Items]                      
Milestone payments $ 19                    
AstraZeneca Agreement                      
License And Collaboration Agreements [Line Items]                      
Milestone payments                 $ 24    
Development cost recorded within research and development expenses         4 1 10 6      
Other liabilities         22   22        
Other current liabilities         10   10        
Other noncurrent liabilities         12   12       11
Gilead Collaboration Agreement                      
License And Collaboration Agreements [Line Items]                      
Other noncurrent assets                     $ 6
Development cost recorded within research and development expenses             6        
Exelixis Collaboration                      
License And Collaboration Agreements [Line Items]                      
Research and development expense         2 1 5 1      
Taiho Pharmaceutical Co., Ltd | Taiho Agreement                      
License And Collaboration Agreements [Line Items]                      
Option period                   5 years  
Non refundable and non creditable cash payments                   $ 35  
Payment for option exercise   $ 15     15            
Royalties payable term                   10 years  
Total revenues         18 4 25 4      
Reimbursement of research and development expense         3 2 10 4      
Taiho Pharmaceutical Co., Ltd | Taiho Agreement | Minimum                      
License And Collaboration Agreements [Line Items]                      
Payment for option exercise                   $ 3  
Taiho Pharmaceutical Co., Ltd | Taiho Agreement | Maximum                      
License And Collaboration Agreements [Line Items]                      
Payment for option exercise                   15  
Additional clinical and regulatory milestone payments receivable                   130  
Contingent milestone payments receivable                   $ 145  
STAR-221 Development Activities | Taiho Collaboration Agreement                      
License And Collaboration Agreements [Line Items]                      
Payment for option exercise             28        
STAR-121 Development Activities | Taiho Collaboration Agreement                      
License And Collaboration Agreements [Line Items]                      
Payment for option exercise     $ 26                
Revenue recognized from amounts in deferred revenue at the beginning of the period             16        
STAR-121 Development Activities | Taiho Collaboration Agreement | Forecast                      
License And Collaboration Agreements [Line Items]                      
Revenue recognized from amounts in deferred revenue at the beginning of the period       $ 10              
WuXi Biologics License Agreement | anti-CD39 | Research and Development                      
License And Collaboration Agreements [Line Items]                      
Development milestone expense         $ 0 $ 0 0 $ 1      
WuXi Biologics License Agreement | Maximum | anti-PD-1                      
License And Collaboration Agreements [Line Items]                      
Clinical regulatory milestone payments             50        
Clinical, regulatory and commercialization milestone payments             375        
WuXi Biologics License Agreement | Maximum | anti-CD39                      
License And Collaboration Agreements [Line Items]                      
Additional clinical, regulatory and commercialization milestone payments             14        
Abmuno License Agreement                      
License And Collaboration Agreements [Line Items]                      
Additional clinical, regulatory and commercialization milestone payments             $ 88