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License and Collaborations - Additional Information (Details) - USD ($)
$ in Millions
1 Months Ended 3 Months Ended 6 Months Ended 12 Months Ended
Jan. 31, 2024
Mar. 31, 2025
Mar. 31, 2024
Sep. 30, 2023
Mar. 31, 2023
Jun. 30, 2018
Dec. 31, 2017
Dec. 31, 2023
Dec. 31, 2018
License And Collaboration Agreements [Line Items]                  
Total revenues     $ 145   $ 25        
Receivable from collaboration partners ($21 and $20 from a related party)     35         $ 38  
Other current liabilities     64         76  
Other noncurrent liabilities     140         142  
Other noncurrent assets ($— and $6 from a related party)     78         106  
Research and development (Net of recoveries of $16 and $33 from a related party)     109   81        
Taiho Collaboration Agreement                  
License And Collaboration Agreements [Line Items]                  
Total revenues     4            
Receivable from collaboration partners ($21 and $20 from a related party)     10         14  
AstraZeneca Agreement                  
License And Collaboration Agreements [Line Items]                  
Milestone payments     24            
Development cost recorded within research and development expenses     3   2        
Other current liabilities     2            
Other noncurrent liabilities     12         11  
Gilead Collaboration Agreement                  
License And Collaboration Agreements [Line Items]                  
Development cost recorded within research and development expenses     6            
Other noncurrent assets ($— and $6 from a related party)               $ 6  
Exelixis Collaboration                  
License And Collaboration Agreements [Line Items]                  
Research and development (Net of recoveries of $16 and $33 from a related party)     1            
Taiho Pharmaceutical Co., Ltd | Taiho Agreement                  
License And Collaboration Agreements [Line Items]                  
Option period           5 years      
Non refundable and non creditable cash payments           $ 35      
Royalties payable term             10 years    
Total revenues     4            
Reimbursement of research and development expense     3            
Taiho Pharmaceutical Co., Ltd | Taiho Agreement | Minimum                  
License And Collaboration Agreements [Line Items]                  
Payment for option exercise           3      
Taiho Pharmaceutical Co., Ltd | Taiho Agreement | Maximum                  
License And Collaboration Agreements [Line Items]                  
Payment for option exercise           15      
Additional clinical and regulatory milestone payments receivable           $ 130      
Contingent milestone payments receivable                 $ 145
STAR-221 Development Activities | Taiho Collaboration Agreement                  
License And Collaboration Agreements [Line Items]                  
Payment for option exercise       $ 28          
STAR-121 Development Activities | Taiho Collaboration Agreement                  
License And Collaboration Agreements [Line Items]                  
Payment for option exercise $ 26                
Revenue recognized     16            
STAR-121 Development Activities | Taiho Collaboration Agreement | Forecast                  
License And Collaboration Agreements [Line Items]                  
Revenue recognized   $ 10              
WuXi Biologics License Agreement | anti-CD39 | Research and Development                  
License And Collaboration Agreements [Line Items]                  
Development milestone expense         $ 1        
WuXi Biologics License Agreement | Maximum | anti-PD-1                  
License And Collaboration Agreements [Line Items]                  
Clinical regulatory milestone payments     50            
Clinical, regulatory and commercialization milestone payments     375            
WuXi Biologics License Agreement | Maximum | anti-CD39                  
License And Collaboration Agreements [Line Items]                  
Additional clinical, regulatory and commercialization milestone payments     14            
Abmuno License Agreement                  
License And Collaboration Agreements [Line Items]                  
Additional clinical, regulatory and commercialization milestone payments     $ 88