Net Loss per Share (Tables)

3 Months Ended

Mar. 31, 2021

Computation of Basic and Diluted Net Loss Per Share

The following table sets forth the computation of basic and diluted net loss per share (in thousands, except share and per share data):

	Three Months Ended March 31,
	2021			2020
Numerator:
Net loss	$	(72,593	)	$	(27,753	)
Denominator:
Weighted-average common shares outstanding		68,476,799			45,953,213
Less: weighted-average common shares subject to vesting		(1,394,638	)		(1,670,606	)
Weighted-average common shares used to compute basic and diluted net loss per share		67,082,161			44,282,607
Net loss per share: basic and diluted	$	(1.08	)	$	(0.63	)

Summary of Outstanding Potentially Dilutive Securities Excluded from Computation of Diluted Net Loss per Share

The following outstanding potentially dilutive securities were excluded from the computation of diluted net loss per share because including them would have been antidilutive:

	Three Months Ended March 31,
	2021		2020
Common stock options issued and outstanding		11,708,625		6,725,835
Unvested restricted common stock issued as part of collaboration agreement		1,257,651		1,257,651
Unvested early exercised common stock options		111,094		375,615
Unvested restricted stock units		1,532,162		-
Employee Stock Purchase Plan shares		96,591		-
Total		14,706,123		8,359,101