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Stock Plans and Stock-Based Compensation - Additional Information (Details) - USD ($)
1 Months Ended 12 Months Ended
Jan. 01, 2021
Jan. 01, 2019
Mar. 31, 2018
Dec. 31, 2020
Dec. 31, 2019
Dec. 31, 2018
Dec. 31, 2015
Nov. 30, 2020
Jan. 31, 2020
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                  
Intrinsic value of shares exercised       $ 6,800,000 $ 200,000 $ 600,000      
Fair value of shares vested       $ 16,800,000 $ 7,800,000 $ 3,000,000.0      
Options granted       5,784,550          
Common stock, shares outstanding       65,114,685 45,925,004        
Share-based compensation, vested stock options       31,986 372,774 14,918      
Description of expected term simplified method       The Company has opted to use the “simplified method” for estimating the expected term of options, whereby the expected term equals the arithmetic average of the vesting term and the original contractual term of the option (generally 10 years).          
Expected term       10 years          
Expected dividend yield       0.00%          
Restricted Stock Units                  
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                  
Award vesting period             4 years    
Estimated fair value, price per share             $ 0.0004    
Vesting interval period             monthly    
Options granted       0 0 0      
Total grant date fair value of shares granted       $ 21,100,000 $ 0 $ 0      
Total grant date fair value of shares vested       100,000 $ 0 $ 0      
Unrecognized employee compensation costs       $ 88,900,000          
Non-vested stock option recognized weighted average period       2 years 10 months 24 days          
Restricted Stock Units | Chief Executive Officer and President                  
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                  
Shares issued             2,777,776    
Price per share             $ 0.0004    
Non-Employee Stock-Based Compensation                  
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                  
Shares not vested and subject to repurchase       21,165 308,596 31,388      
Stock based compensation expense       $ 700,000 $ 900,000 $ 300,000      
Employee Stock Option                  
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                  
Unrecognized employee compensation costs       $ 88,900,000          
Non-vested stock option recognized weighted average period       2 years 10 months 24 days          
Expected term       6 years 7 days 6 years 7 days        
Expected dividend yield       0.00% 0.00% 0.00%      
Maximum | Employee Stock Option                  
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                  
Expected term           9 years 11 months 12 days      
Minimum | Employee Stock Option                  
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                  
Expected term           5 years 1 month 28 days      
2015 Stock Plan                  
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                  
Shares not vested and subject to repurchase       165,133 455,158        
Cash received from early exercise of unvested options       $ 700,000 $ 1,700,000        
Award vesting period       48 months          
Total shares of authorized common stock reserved for future issuance     709,558            
2018 Equity Incentive Plan                  
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                  
Number of shares issued or transferred     3,570,000            
Total shares of authorized common stock reserved for future issuance       1,106,209          
2018 Equity Incentive Plan | Restricted Stock Units                  
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                  
Shares not vested and subject to repurchase       738,650          
2018 Equity Incentive Plan | Restricted Stock Units | Employees                  
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                  
Award vesting period       4 years          
Vesting interval period       annually or quarterly          
2018 Equity Incentive Plan | Restricted Stock Units | Directors                  
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                  
Vesting interval period       annually          
2018 Equity Incentive Plan | Subsequent Event                  
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                  
Shares of common stock reserved for issuance under evergreen provision 2,604,587                
2018 Equity Incentive Plan | Maximum                  
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                  
Shares of common stock reserved for issuance under evergreen provision   3,570,000              
Percentage of common stock outstanding   4.00%              
2020 Inducement Plan                  
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                  
Number of shares issued or transferred               1,000,000 3,000,000
Total shares of authorized common stock reserved for future issuance       784,975          
2018 Employee Stock Purchase Plan                  
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                  
Purchase date of fair market value trading days     24 months            
Total shares of authorized common stock reserved for future issuance     714,000 1,190,422          
2018 Employee Stock Purchase Plan | Subsequent Event                  
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                  
Shares of common stock reserved for issuance under evergreen provision 651,146                
2018 Employee Stock Purchase Plan | Maximum                  
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                  
Purchase price of common stock as percentage of market value     85.00%            
Number of shares of common stock that may be purchased by an employee on any purchase date     3,000            
Number of shares that may be purchased in any calendar year     $ 25,000            
Percentage of common stock shares outstanding   1.00%              
Common stock, shares outstanding   1,071,000