Net Loss per Share

12 Months Ended

Dec. 31, 2020

Note 10. Net Loss per Share

The following table sets forth the computation of basic and diluted net loss per share (in thousands, except share and per share data):

	Year Ended December 31,
	2020			2019			2018
Numerator:
Net loss	$	(122,858	)	$	(84,710	)	$	(49,594	)
Denominator:
Weighted-average common shares outstanding		56,354,059			45,385,489			36,357,336
Less: weighted-average common shares subject to repurchase		(1,566,941	)		(1,559,498	)		(1,739,099	)
Weighted-average common shares used to compute basic and diluted net loss per share		54,787,118			43,825,991			34,618,237
Net loss per share, basic and diluted	$	(2.24	)	$	(1.93	)	$	(1.43	)

The following outstanding potentially dilutive securities were excluded from the computation of diluted net loss per share for the periods presented because including them would have been antidilutive:

	At December 31,
	2020		2019		2018
Common stock options issued and outstanding		9,892,697		4,738,004		1,458,079
Unvested restricted stock issued as part of collaboration agreement		1,257,651		1,257,651		-
Unvested early exercised common stock options		165,133		455,158		927,123
Unvested restricted stock units		738,650		-		-
Employee Stock Purchase Plan shares		18,219		-		-
Unvested restricted common stock		-		-		289,352
Total		12,072,350		6,450,813		2,674,554