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License and Collaboration Agreements - Additional Information (Details)
1 Months Ended 3 Months Ended 9 Months Ended 12 Months Ended 17 Months Ended 38 Months Ended
Jul. 13, 2020
USD ($)
$ / shares
shares
Apr. 30, 2019
USD ($)
shares
Oct. 31, 2017
USD ($)
Sep. 30, 2017
USD ($)
Program
Aug. 31, 2017
USD ($)
Sep. 30, 2020
USD ($)
shares
Jun. 30, 2020
USD ($)
Sep. 30, 2019
USD ($)
Sep. 30, 2020
USD ($)
shares
Sep. 30, 2019
USD ($)
Dec. 31, 2019
USD ($)
Dec. 31, 2018
USD ($)
Dec. 31, 2017
USD ($)
Sep. 30, 2020
USD ($)
shares
Sep. 30, 2020
USD ($)
shares
License And Collaboration Agreements [Line Items]                              
Upfront cash payment                 $ 175,000,000            
Issuance of common stock             $ 326,246,000                
Cost sharing receivable, current           $ 2,579,000     2,579,000   $ 132,000 [1]     $ 2,579,000 $ 2,579,000
Development expense           51,801,000   $ 17,241,000 110,636,000 $ 57,795,000          
Compensation expense recognized           6,002,000   2,740,000 13,934,000 6,544,000          
Research and Development Expenses                              
License And Collaboration Agreements [Line Items]                              
Compensation expense recognized           3,075,000   $ 978,000 7,179,000 $ 2,693,000          
Stock Purchase Agreement                              
License And Collaboration Agreements [Line Items]                              
Direct offering cost $ 1,900,000                            
Development And Commercialization Services                              
License And Collaboration Agreements [Line Items]                              
Reimbursed under cost-sharing arrangement           500,000                  
Gilead | Gilead Collaboration Agreement                              
License And Collaboration Agreements [Line Items]                              
Upfront cash payment 175,000,000.0               175,000,000            
Unconstrained consideration to be received           100,000,000     100,000,000         100,000,000 100,000,000
Premium on stock purchased $ 90,600,000                            
Present value of unconstrained consideration                 99,100,000            
Collaboration term for current and future clinical programs 10 years                            
Contingent milestone payments receivable $ 400,000,000.0                            
Additional collaboration term for programs entering clinical development prior to end of collaboration term 3 years                            
Option fee per program for all other programs entering clinical development to exercise option $ 150,000,000                            
Ongoing research and development support 400,000,000                            
Present value of research and development information access rights payment related to year 2022 100,000,000.0                            
Initial transaction price 364,700,000                            
Option payment upon achievement of certain development milestones 250,000,000.0                            
Option payment upon achievement of certain development milestones $ 275,000,000.0                            
Current and future programs exclusive access period 10 years                            
Additional payment due at each of the fourth, sixth, and eighth anniversaries of the agreement $ 100,000,000                            
Contingent milestone payment start period 2022                            
Contractual obligation for first payment $ 100,000,000.0                            
Performance obligation period 4 years                            
Contractual obligation remaining amount not obligated to pay $ 300,000,000.0                            
Consultant and legal fees 7,300,000                            
Amortization expense           1,100,000     1,100,000            
Cost sharing receivable           4,300,000     4,300,000         4,300,000 4,300,000
Future development and promotion costs contract liability 9,200,000                            
Sub-license fees incurred 10,100,000                            
Gilead | Gilead Collaboration Agreement | Other Current Liabilities                              
License And Collaboration Agreements [Line Items]                              
Future development and promotion costs contract liability current           1,900,000     1,900,000         1,900,000 1,900,000
Gilead | Gilead Collaboration Agreement | Prepaid Expenses and Other Current Assets                              
License And Collaboration Agreements [Line Items]                              
Cost sharing receivable, current 2,900,000                            
Gilead | Gilead Collaboration Agreement | Other Noncurrent Liabilities                              
License And Collaboration Agreements [Line Items]                              
Future development and promotion costs contract liability noncurrent           7,300,000     7,300,000         7,300,000 7,300,000
Gilead | Gilead Collaboration Agreement | Other Noncurrent Assets                              
License And Collaboration Agreements [Line Items]                              
Cost sharing receivable, noncurrent 1,400,000                            
Gilead | Gilead Collaboration Agreement | Minimum                              
License And Collaboration Agreements [Line Items]                              
Option fee per program for current clinical programs to exercise option 200,000,000                            
Gilead | Gilead Collaboration Agreement | Maximum                              
License And Collaboration Agreements [Line Items]                              
Contingent milestone payments receivable 400,000,000.0                            
Option fee per program for current clinical programs to exercise option 275,000,000                            
Gilead | Stock Purchase Agreement                              
License And Collaboration Agreements [Line Items]                              
Funds received for purchase of common stock                 200,000,000            
Fair value of stock purchased                 109,400,000            
Premium on stock purchased                 $ 90,600,000            
Issuance of common stock $ 200,000,000         107,468,000                  
Issuance of common stock, shares | shares 5,963,029                            
Shares Issued, Price Per Share | $ / shares $ 33.54                            
Percentage of option to purchase maximum shares of common stock 35.00%                            
Period over common stock to be purchased 5 years                            
Percentage of premium purchase price of common stock 20.00%                            
Trailing days average closing price 5 days                            
Share Price | $ / shares $ 33.54                            
Taiho Pharmaceutical Co., Ltd | Taiho Agreement                              
License And Collaboration Agreements [Line Items]                              
Upfront cash payment       $ 20,000,000.0                      
Option period       5 years                      
Non refundable and non creditable cash payments       $ 35,000,000.0                      
Payment received for license agreement     $ 5,000,000.0               5,000,000.0 $ 5,000,000.0 $ 25,000,000.0    
Range of royalties receivable on net sales                 high single-digits to mid-teens            
Royalties payable description                 Royalties will be payable on a licensed product-by-licensed product and country-by-country basis during the period of time commencing on the first commercial sale of a licensed product in a country and ending upon the later of: (a) ten (10) years from the date of first commercial sale of such licensed product in such country; and (b) expiration of the last-to-expire valid claim of the Company’s patents covering the manufacture, use or sale or exploitation of such licensed product in such country (the Royalty Term).            
Non-refundable, non-creditable upfront cash payments                 $ 35,000,000.0            
Estimated performance period                 5 years            
Payment for first option exercise                     8,000,000.0 $ 3,000,000.0      
Licensing revenue recognized                     $ 8,000,000.0        
Clinical and regulatory milestones achieved                 $ 0            
Sales milestone or royalty revenue recognized                 $ 0            
Taiho Pharmaceutical Co., Ltd | Taiho Agreement | Minimum                              
License And Collaboration Agreements [Line Items]                              
Number of programs, IND enabling studies not initiated | Program       5                      
Payment for option exercise       $ 3,000,000.0                      
Taiho Pharmaceutical Co., Ltd | Taiho Agreement | Maximum                              
License And Collaboration Agreements [Line Items]                              
Contingent milestone payments receivable       $ 145,000,000.0                      
Extended option agreement period       7 years                      
Payment for option exercise       $ 15,000,000.0                      
Additional clinical and regulatory milestone payments receivable       $ 130,000,000.0                      
WuXi Biologics License Agreement                              
License And Collaboration Agreements [Line Items]                              
Range of tiered royalty payments on net sales                 high single-digits to low teens            
Development expense           10,100,000     $ 15,100,000            
Development milestone expense                 5,000,000.0            
WuXi Biologics License Agreement | Research and Development Expenses                              
License And Collaboration Agreements [Line Items]                              
Sub-license fees incurred                             11,300,000
Upfront and milestone payments                             $ 31,000,000.0
WuXi Biologics License Agreement | Maximum                              
License And Collaboration Agreements [Line Items]                              
Clinical, regulatory and commercialization milestone payments         $ 375,000,000.0                    
Abmuno License Agreement                              
License And Collaboration Agreements [Line Items]                              
Upfront and milestone payments                 9,600,000            
Development milestone expense           3,000,000.0     3,000,000.0            
Clinical, regulatory and commercialization remaining milestone payments                 98,000,000.0            
Genentech                              
License And Collaboration Agreements [Line Items]                              
Development expense           100,000     100,000            
Strata Oncology Inc | Strata Agreement                              
License And Collaboration Agreements [Line Items]                              
Reimbursed under cost-sharing arrangement           100,000     200,000         400,000  
Development milestone payable   $ 2,500,000                          
Development cost recorded within research and development expenses           $ 300,000     $ 1,200,000         $ 2,200,000  
Number of restricted shares of common stock issued | shares   1,257,651                          
Fair value of restricted shares of common stock issued   $ 15,000,000.0                          
Strata Oncology Inc | Strata Agreement | Non-vested Restricted Stock                              
License And Collaboration Agreements [Line Items]                              
Shares probable of vesting | shares           0     0         0 0
Compensation expense recognized                 $ 0            
Strata Oncology Inc | Strata Agreement | Research and Development Expenses                              
License And Collaboration Agreements [Line Items]                              
Milestone payments                           $ 2,500,000  
Strata Oncology Inc | Strata Agreement | Maximum                              
License And Collaboration Agreements [Line Items]                              
Regulatory and commercial milestone payable   $ 125,000,000.0                          
[1] The Condensed Consolidated Balance Sheet as of December 31, 2019 has been derived from the audited financial statements as of that date.