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Net Loss per Share - Computation of Basic and Diluted Net Loss Per Share (Details) - USD ($)
$ / shares in Units, $ in Thousands
3 Months Ended 9 Months Ended
Sep. 30, 2019
Jun. 30, 2019
Mar. 31, 2019
Sep. 30, 2018
Jun. 30, 2018
Mar. 31, 2018
Sep. 30, 2019
Sep. 30, 2018
Numerator:                
Net loss $ (22,352) $ (28,090) $ (17,670) $ (10,812) $ (13,533) $ (12,955) $ (68,112) $ (37,299)
Denominator:                
Weighted-average common shares outstanding 45,787,137     44,452,184     45,253,176 33,937,800
Less: weighted-average common shares subject to vesting (1,847,856)     (1,614,086)     (1,503,022) (1,881,125)
Weighted-average number of shares used to compute basic and diluted net loss per share 43,939,281     42,838,098     43,750,154 32,056,675
Net loss per share: basic and diluted $ (0.51)     $ (0.25)     $ (1.56) $ (1.16)