Summary of Significant Accounting Policies (Tables)

9 Months Ended

Sep. 30, 2019

Significant Accounting Policies [Line Items]

The impact of the adoption of Topic 606 on contract liabilities and accumulated deficit balances as of January 1, 2019 was as follows (in thousands):

	December 31, 2018			Adjustment Due to the Adoption of Topic 606			January 1, 2019
Current portion of deferred revenue	$	6,250		$	750		$	7,000
Long-term portion of deferred revenue		16,984			(2,962	)		14,022
Accumulated deficit	$	(122,828	)	$	2,212		$	(120,616	)

The impact of the adoption of Topic 606 on the Company’s Condensed Consolidated Balance Sheet and Statement of Operations as of and for the period ended September 30, 2019 was as follows (in thousands):

	As of September 30, 2019
	As Reported		Balances without the Adoption of Topic 606		Effect of Adoption Higher/ (Lower)
Current portion of deferred revenue	$	7,000	$	7,917	$	(917	)
Long-term portion of deferred revenue		13,772		15,574		(1,802	)
Accumulated deficit	$	—	$	—	$	(2,399	)

	Three Months Ended September 30, 2019
	As Reported			Without the Adoption of Topic 606			Effect of Adoption Higher/ (Lower)
Collaboration revenues	$	1,750		$	1,618		$	132
Net loss		(22,352	)		(22,484	)	$	132
Net loss per share, basic and diluted	$	(0.51	)	$	(0.51	)	$	—

	Nine Months Ended September 30, 2019
	As Reported			Without the Adoption of Topic 606			Effect of Adoption Higher/ (Lower)
Collaboration revenues	$	5,250		$	4,743		$	507
Net loss		(68,112	)		(68,619	)	$	507
Net loss per share, basic and diluted	$	(1.56	)	$	(1.57	)	$	—

ASU 2016-18

Significant Accounting Policies [Line Items]

Impact of Adoption

The following table provides a reconciliation of cash, cash equivalents and restricted cash reported within the condensed consolidated balance sheets that sum to the total of the same such amount shown on the condensed consolidated statements of cash flows (in thousands):

	September 30, 2019		December 31, 2018		September 30, 2018		December 31, 2017
Cash and cash equivalents	$	78,992	$	71,064	$	74,889	$	98,426
Restricted cash		203		203		203		203
Cash, cash equivalents and restricted cash	$	79,195	$	71,267	$	75,092	$	98,629