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Net Loss per Share - Computation of Basic and Diluted Net Loss Per Share (Details) - USD ($)
$ / shares in Units, $ in Thousands
3 Months Ended 6 Months Ended
Jun. 30, 2019
Mar. 31, 2019
Jun. 30, 2018
Mar. 31, 2018
Jun. 30, 2019
Jun. 30, 2018
Numerator:            
Net loss $ (28,090) $ (17,670) $ (13,533) $ (12,955) $ (45,760) $ (26,488)
Denominator:            
Weighted-average common shares outstanding 45,409,588   44,450,312   44,970,831 28,248,337
Less: weighted-average common shares subject to vesting (1,611,870)   (1,916,671)   (1,317,506) (2,012,330)
Weighted-average number of shares used to compute basic and diluted net loss per share 43,797,718   42,533,641   43,653,325 26,236,007
Net loss per share: basic and diluted $ (0.64)   $ (0.32)   $ (1.05) $ (1.01)