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Net Loss per Share - Computation of Basic and Diluted Net Loss Per Share (Details) - USD ($)
$ / shares in Units, $ in Thousands
3 Months Ended 9 Months Ended
Sep. 30, 2018
Sep. 30, 2017
Sep. 30, 2018
Sep. 30, 2017
Numerator:        
Net loss $ (10,812) $ (23,122) $ (37,299) $ (39,872)
Denominator:        
Weighted-average common shares outstanding 44,452,184 3,994,915 33,937,800 3,816,784
Less: weighted-average common shares subject to repurchase (1,614,086) (2,045,657) (1,881,125) (2,117,739)
Weighted-average number of shares used to compute basic and diluted net loss per share 42,838,098 1,949,258 32,056,675 1,699,045
Net loss per share: basic and diluted $ (0.25) $ (11.86) $ (1.16) $ (23.47)