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Condensed Consolidated Statements of Cash Flows - USD ($)
$ in Millions
6 Months Ended
Jun. 30, 2023
Jun. 30, 2022
Cash flows from operating activities    
Net loss $ (155) $ (135)
Adjustments to reconcile net loss to net cash used in operating activities:    
Stock-based compensation expense 37 32
Depreciation and amortization 4 3
Noncash lease expense 4 4
Amortization of premiums (discounts) on marketable securities (8) 2
Other items, net 1 4
Changes in operating assets and liabilities:    
Receivable from collaboration partners ($7 and $709 from a related party) 4 709
Other assets (($3) and ($1) from a related party) (1) 3
Accounts payable (9) 12
Deferred revenue (($19) and ($42) to a related party) (19) (45)
Other liabilities (13)  
Net cash provided by (used in) operating activities (155) 589
Cash flows from investing activities    
Purchases of marketable securities (393) (763)
Proceeds from maturities of marketable securities 542 263
Proceeds from sales of marketable securities 14 27
Purchases of property and equipment (8) (4)
Purchases of in-process research and development   (6)
Net cash provided by (used in) investing activities 155 (483)
Cash flow from financing activities    
Proceeds from issuance of common stock to a related party 20  
Proceeds from issuance of common stock pursuant to equity award plans 4 14
Proceeds from sale of future royalties   5
Net cash provided by financing activities 24 19
Net increase in cash, cash equivalents and restricted cash 24 125
Cash, cash equivalents and restricted cash at beginning of period 209 151
Cash, cash equivalents and restricted cash at end of period 233 276
Non-cash investing and financing activities:    
Unpaid portion of property and equipment purchases included in accounts payable and accrued liabilities $ 8 $ 1