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Related party - Gilead Sciences, Inc. - Additional Information (Details)
$ / shares in Units, shares in Millions, $ in Millions
1 Months Ended 3 Months Ended 6 Months Ended 12 Months Ended
Jun. 27, 2023
USD ($)
$ / shares
shares
May 12, 2023
USD ($)
Program
Oct. 31, 2022
Jan. 31, 2022
USD ($)
Jun. 30, 2023
USD ($)
$ / shares
Jun. 30, 2022
USD ($)
Jun. 30, 2023
USD ($)
Program
$ / shares
Jun. 30, 2022
USD ($)
Dec. 31, 2021
USD ($)
Program
shares
Dec. 31, 2020
USD ($)
shares
Research and Development                    
Related Party Transaction [Line Items]                    
Reimbursed under cost-sharing provisions of arrangement         $ 34.0 $ 36.0 $ 67.0 $ 66.0    
Gilead Collaboration Agreement                    
Related Party Transaction [Line Items]                    
Option payment upon completion of certain IND-enabling activities             60.0      
Option payment upon achievement of certain development milestones             $ 150.0      
Amended Investor Rights Agreement                    
Related Party Transaction [Line Items]                    
Lockup period     2 years              
Extended lockup period     3 years              
Amended Gilead Collaboration Agreement                    
Related Party Transaction [Line Items]                    
Number of programs, eligible to receive regulatory and commercial milestone payments | Program   2                
Number of exercise option to programs | Program                 3  
Option payments received       $ 725.0            
Removal of option continuation payment under agreement                 $ 100.0  
Option payment upon achievement of certain development milestones   $ 150.0                
Gilead                    
Related Party Transaction [Line Items]                    
Percentage of outstanding common stock held         19.90%   19.90%      
Gilead | Research and Development                    
Related Party Transaction [Line Items]                    
Reimbursed under cost-sharing provisions of arrangement         $ 34.0 36.0 $ 67.0 66.0    
Gilead | Gilead Collaboration Agreement                    
Related Party Transaction [Line Items]                    
Collaboration term for current and future clinical programs                   10 years
Option continuation payment due upon second anniversary of agreement                   $ 100.0
Option continuation payment due upon fourth anniversary of agreement                   100.0
Option continuation payment due upon sixth anniversary of agreement                   100.0
Option Continuation Payment Due Upon Eighth Anniversary of Agreement                   100.0
Upfront cash payment                   175.0
Option fee per program for all other programs entering clinical development to exercise option                   150.0
Number of research programs | Program             2      
Revenue recognized         $ 29.0 $ 26.0 $ 54.0 $ 42.0    
Gilead | Gilead Collaboration Agreement | Maximum                    
Related Party Transaction [Line Items]                    
Potential regulatory approval milestones payment receivable related to domvanalimab                   $ 500.0
Gilead | Stock Purchase Agreement                    
Related Party Transaction [Line Items]                    
Percentage of premium purchase price of common stock             20.00%      
Trailing days average closing price             5 days      
Weighted average closing price of our common stock on grant date | $ / shares $ 19.26       $ 33.54   $ 33.54      
Issuance of common stock, shares | shares 1.0               5.7 6.0
Issuance of common stock $ 20.0               $ 220.0  
Funds received for purchase of common stock                   $ 200.0
Purchase price of common stock allocation to performance obligation                   $ 91.0
Gilead | Stock Purchase Agreement | Maximum                    
Related Party Transaction [Line Items]                    
Right to purchase additional outstanding voting common stock percentage         35.00%   35.00%      
Gilead | Amended Gilead Collaboration Agreement                    
Related Party Transaction [Line Items]                    
Upfront cash payment   17.5         $ 35.0      
Number of research programs | Program             2      
Option payment upon completion of certain IND-enabling activities   45.0                
Gilead | Amended Gilead Collaboration Agreement | Maximum                    
Related Party Transaction [Line Items]                    
Regulatory and commercial milestone payments received   $ 375.0