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License and Collaborations - Additional Information (Details) - USD ($)
3 Months Ended 12 Months Ended
Mar. 31, 2023
Mar. 31, 2022
Dec. 31, 2017
Dec. 31, 2022
License And Collaboration Agreements [Line Items]        
Liabilities classified as noncurrent $ 145,000,000     $ 140,000,000
Shared costs classified as other noncurrent assets 112,000,000     114,000,000
Total collaboration and license revenues 25,000,000 $ 18,000,000    
WuXi Biologics License Agreement | anti-CD39 | Research and Development        
License And Collaboration Agreements [Line Items]        
Development milestone expense 1,000,000 2,000,000    
WuXi Biologics License Agreement | Maximum | anti-PD-1        
License And Collaboration Agreements [Line Items]        
Clinical, regulatory and commercialization milestone payments     $ 375,000,000  
WuXi Biologics License Agreement | Maximum | anti-CD39        
License And Collaboration Agreements [Line Items]        
Additional clinical, regulatory and commercialization milestone payments 14,000,000      
Abmuno License Agreement        
License And Collaboration Agreements [Line Items]        
Additional clinical, regulatory and commercialization milestone payments 88,000,000      
AstraZeneca Agreement        
License And Collaboration Agreements [Line Items]        
Liabilities classified as noncurrent 7,000,000     5,000,000
Development cost recorded within research and development expenses $ 2,000,000 1,000,000    
Taiho Agreement | Taiho Pharmaceutical Co., Ltd        
License And Collaboration Agreements [Line Items]        
Option period     5 years  
Option ending period     2022-09  
Non refundable and non creditable cash payments     $ 35,000,000  
Range of royalties receivable on net sales high single-digits to mid-teens      
Royalties payable description Royalties will be payable by product and country commencing on the first commercial sale and ending upon the later of: (a) 10 years; and (b) expiration of the last-to-expire valid claim of our patents covering the manufacture, use or sale.      
Total collaboration and license revenues   2,000,000    
Deferred revenue   $ 0    
Taiho Agreement | Taiho Pharmaceutical Co., Ltd | Minimum        
License And Collaboration Agreements [Line Items]        
Payment for option exercise     3,000,000  
Taiho Agreement | Taiho Pharmaceutical Co., Ltd | Maximum        
License And Collaboration Agreements [Line Items]        
Contingent milestone payments receivable     145,000,000  
Payment for option exercise     15,000,000  
Additional clinical and regulatory milestone payments receivable     $ 130,000,000  
Option License And Collaboration Agreement [Member]        
License And Collaboration Agreements [Line Items]        
Shared costs classified as other noncurrent assets $ 3,000,000     2,000,000
Deferred revenue $ 427,000,000     $ 452,000,000