Liability for Sale of Future Royalties - Additional Information (Details) - BVF Partners L.P. - BVF Agreement - USD ($)	12 Months Ended
Dec. 31, 2022	Dec. 31, 2021
Research and Development Arrangement, Contract to Perform for Others [Line Items]
Imputed effective rate of interest on unamortized portion of liability	20.60%
Maximum
Research and Development Arrangement, Contract to Perform for Others [Line Items]
Contingent payments upon achievement of certain clinical and regulatory milestones		$ 73,000,000

Line items represent financial concepts included in a table. These concepts are used to disclose reportable information associated with domain members defined in one or many axes to the table.

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