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Net Income (Loss) per Share - Summary of Outstanding Potentially Dilutive Securities Excluded from Computation of Diluted Net Income (Loss) per Share (Details) - shares
12 Months Ended
Dec. 31, 2022
Dec. 31, 2021
Dec. 31, 2020
Antidilutive Securities Excluded From Computation Of Earnings Per Share [Line Items]      
Antidilutive securities excluded from computation of diluted net loss per share 13,500,000 4,600,000 12,100,000
Common Stock Options Issued and Outstanding      
Antidilutive Securities Excluded From Computation Of Earnings Per Share [Line Items]      
Antidilutive securities excluded from computation of diluted net loss per share 12,000,000.0 4,500,000 9,900,000
Restricted Stock Units Issued      
Antidilutive Securities Excluded From Computation Of Earnings Per Share [Line Items]      
Antidilutive securities excluded from computation of diluted net loss per share 1,300,000   700,000
Unvested Early Exercised Common Stock Options      
Antidilutive Securities Excluded From Computation Of Earnings Per Share [Line Items]      
Antidilutive securities excluded from computation of diluted net loss per share     200,000
Employee Stock Purchase Plan Shares      
Antidilutive Securities Excluded From Computation Of Earnings Per Share [Line Items]      
Antidilutive securities excluded from computation of diluted net loss per share 200,000 100,000  
Unvested Restricted Stock Issued as Part of Collaboration Agreement      
Antidilutive Securities Excluded From Computation Of Earnings Per Share [Line Items]      
Antidilutive securities excluded from computation of diluted net loss per share     1,300,000