License and Collaboration Agreements - Summary of Revenues (Details) - Gilead and Taiho - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2021	Dec. 31, 2020	Dec. 31, 2019
License
License And Collaboration Agreements [Line Items]
Total collaboration and license revenues	$ 343,838	$ 55,096	$ 8,000
License and Development Services Revenue
License And Collaboration Agreements [Line Items]
Total collaboration and license revenues	1,135
Other Collaboration Revenue
License And Collaboration Agreements [Line Items]
Total collaboration and license revenues	37,909	22,421	7,000
Collaboration and License
License And Collaboration Agreements [Line Items]
Total collaboration and license revenues	$ 382,882	$ 77,517	$ 15,000