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Funding Arrangements (Details) - USD ($)
1 Months Ended 3 Months Ended 8 Months Ended 9 Months Ended
Sep. 30, 2019
Dec. 31, 2016
Sep. 30, 2019
Sep. 30, 2018
Oct. 31, 2017
Sep. 30, 2019
Sep. 30, 2018
Dec. 31, 2018
USAMRAA grant                
Funding Arrangements                
Maximum reimbursable research expenditures   $ 1,100,000            
Grant income recognized     $ 0 $ 100,000   $ 37,000 $ 400,000  
Funds received during the period           200,000 700,000  
Grants receivable $ 0   0     0   $ 200,000
CARB-X program                
Funding Arrangements                
Grant income recognized     600,000 $ 1,500,000   1,800,000 4,100,000  
Funds received during the period           2,000,000 $ 1,900,000  
Grants receivable 1,300,000   $ 1,300,000     $ 1,300,000   $ 1,500,000
Minimum | CARB-X program                
Funding Arrangements                
Reimbursable research expenditures         $ 16,400,000      
Maximum | CARB-X program                
Funding Arrangements                
Reimbursable research expenditures $ 16,800,000