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License and Collaboration Agreements (Details) - USD ($)
$ in Thousands
1 Months Ended 3 Months Ended 6 Months Ended 15 Months Ended
Apr. 30, 2018
Jun. 30, 2019
Jun. 30, 2018
Jun. 30, 2019
Jun. 30, 2018
Jun. 30, 2019
License and Collaboration Agreement with Zai Lab            
Revenue     $ 5,000   $ 5,000  
License and collaboration agreement with Zai Lab            
License and Collaboration Agreement with Zai Lab            
Upfront, non-refundable payment received, net of tax $ 5,000         $ 5,000
Upfront, non-refundable research support funding, net of tax           600
Upfront, non-refundable certain other reimbursable clinical trial costs           300
Upfront, non-refundable payment received, tax expense           800
Eligible amount receivable in research and development support payments and development, regulatory and sales milestone payments   $ 98,000   $ 98,000   $ 98,000
Revenue   $ 0   $ 0 $ 5,000