CONSOLIDATED STATEMENTS OF OPERATIONS AND COMPREHENSIVE LOSS - USD ($) $ in Thousands	3 Months Ended
	Mar. 31, 2019	Mar. 31, 2018
Operating expenses:
Research and development	$ 11,002	$ 8,550
General and administrative	3,189	3,218
Total operating expenses	14,191	11,768
Loss from operations	(14,191)	(11,768)
Other income:
Grant income	829	1,089
Interest income	492	12
Total other income	1,321	1,101
Loss before income taxes	(12,870)	(10,667)
Provision for income taxes	71
Net loss	$ (12,941)	$ (10,667)
Net Loss per Share
Net loss per share attributable to common stockholders—basic and diluted (in dollar per share)	$ (0.99)	$ (844.01)
Weighted average common stock outstanding—basic and diluted (in shares)	13,126,595	12,639
Other comprehensive loss
Net loss	$ (12,941)	$ (10,667)
Net unrealized loss on investments held	43
Foreign currency translation adjustments		(44)
Comprehensive loss	$ (12,898)	$ (10,711)