Exhibit 4.11

CERTAIN CONFIDENTIAL INFORMATION CONTAINED IN THIS DOCUMENT, MARKED BY […***…], HAS BEEN OMITTED BECAUSE ASLAN PHARMACEUTICALS PTE LTD. HAS DETERMINED THE INFORMATION (I) IS NOT MATERIAL AND (II) WOULD LIKELY CAUSE COMPETITIVE HARM TO ASLAN PHARMACEUTICALS PTE LTD. IF PUBLICLY DISCLOSED.

LICENCE AGREEMENT

FOR ASLAN003

BETWEEN

ASLAN Pharmaceuticals Pte Ltd

AND

BioGenetics Co., Ltd.

Dated: 11^th March 2019

THIS AGREEMENT is made on2019

BETWEEN:-

(1) ASLAN PHARMACEUTICALS PTE. LTD. (“ASLAN”), incorporatedandregisteredinSingaporewithcompanynumber201007695N,having its principal offices at 83 Clemenceau Avenue, #12-03 UE Square, Singapore 239920; and

(2) BIOGENETICS CO., LTD. (“BIOGENETICS”), a Republic of Korea corporation having its principal offices at 11^th Liveplex Tower, 702 Eonju-ro, Gangnam-gu, Seoul, Republic of Korea.

WHEREAS:-

A.ASLAN owns, and has a master licence from Almirall S.A. for, certain intellectual property rights and know-how with respect to that certain chemical compound designated by ASLAN as ASLAN003, and believes that ASLAN003 has the potential to become a therapeutic drug with significant commercial potential.

B.ASLAN desires to find a partner capable of realizing promptly the therapeutic and commercial potential of Products in the Territory and within the Field (terms as defined below).

C.BIOGENETICS possesses pharmaceutical development capabilities, and desires to collaborate with ASLAN to develop the therapeutic and commercial potential of Products in the Territory.

D.Now, therefore, in consideration of the premises and mutual covenants herein contained, and for other good and valuable consideration, the receipt and sufficiency of which are hereby acknowledged, the Parties hereto agree as follows:

1. DEFINITIONS AND INTERPRETATION

1.1. ThedefinitionsandrulesofinterpretationinthisSectionapplyinthisAgreement:

"Affiliate"shall mean, with respect to a legal entity, any corporation or other entity which directly or indirectly Controls, is Controlled by or is under common Control with, such entity.

“Almirall Head Licence Agreement” shall mean a licence agreement between ASLAN and Almirall S.A. originally dated 16th May 2012 and most recently re-stated in amended form on 16th March 2018 which grants exclusive worldwide rights over ASLAN003 to ASLAN.

“ASLAN003” shall mean the synthetic chemical entity identified as […***…] by its ultimate owner Almirall SA and identified by ASLAN as ASLAN003, which is an inhibitor of human dihydroorotate dehydrogenase and Improvements thereto made during the Term of this Agreement.

“ASLANIn-LicensedKnow-How”meansallresults,data,know-how,compounds,processes,discoveries,formulations,materials,inventions,techniquesorproprietaryconfidentialinformationwhich:

(a) are necessary for manufacturing, applying for and obtaining marketing authorisations or licences in respect of, marketing or selling Products; and

(b) are licensed to ASLAN pursuant to the Almirall Head Licence Agreement in respect of which, and to the extent that, ASLAN is entitled to grant a sub-licence of such know-how.

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“ASLAN In-Licensed Patents” means patents and patent applications listed in Schedule 1 part (i) licensed to ASLAN at the date of the Agreement pursuant to the Almirall Head Licence Agreement, to the extent that ASLAN is entitled to grant sub-licences of the same, and to the extent that they relate to the Commercialization of Products, to the extent that ASLAN is entitled to grant sub-licences of the same.

"ASLANKnow-How"shallmeanallresults,data,know-how, compounds,processes,discoveries,formulations,materials,inventions,techniquesorproprietaryconfidentialinformationwhich:

(a) arenecessaryforresearching,developing,manufacturing,applyingforandobtainingmarketingauthorisationsorlicencesinrespectof,marketingorsellingProducts;and

(b) areowned or Controlled byASLANasatthedateofthisAgreement.

"ASLANPatents"shallmeanthepatents and patent applications owned or ControlledbyASLAN relating to ASLAN003 andlistedinSchedule1 parts (i) and (ii), and any other patents and patent applications relating to Products Controlled by ASLAN from time to time during the Licence Period covering the Territory.

“BusinessDay”meansadaythatisnotaSaturday,SundayorpublicholidayinSingaporeorthe Republic of Korea.

“Claim”means,inrelationtoaperson,ademand,claim,actionorproceedingmadeorbroughtbyoragainsttheperson,howeverarising.

“Commercialize”means use, apply for or obtain marketing authorizations or licences, import, sell, have sold, promote, market or distribute, and, if agreed in accordance with Section 4.2, manufacture, have manufactured, make and have made; and "Commercialization" shall be construed accordingly;

"Commercially Reasonable Efforts"shallmeanthecarryingoutofobligationsortasksinareasonable,goodfaith,anddiligentmannerconsistentwitheffortsandresourcesascommonlyusedbyacompanywithexperienceandexpertiseinthedevelopmentandcommercializationofpharmaceuticalproducts, in such a company’s ordinary course of business,forapharmaceuticalproductatasimilarstageofresearchanddevelopment,andhavingsimilarmarketpotentialtotheProduct,takingintoaccount,withoutlimitation,issuesofsafety,efficacy,productprofile,statusoftheProduct,thedevelopmentcosts,theregulatoryenvironment,andotherscientificfactors,marketconditionsthenprevailing,includingcompetitiveenvironment,profitabilitythecompetitivenessofalternative productsthatareorareexpectedtobeintherelevantmarketplace,andothersimilarfactors.

“Competing Product” means any product which is intended to be used for the treatment of same disease indications as Products (now or in the future) by means of an agent that has the same mechanism of action (DHODH inhibitor) as ASLAN003.

“ConfidentialInformation”hasthemeaninggiventoitinSection10.1.

"Control,""Controls," "Controlled"or "Controlling"shallmean:

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(a) inrelationtoalegalentity,thepossession,directlyorindirectly,ofmorethan50% ofthe issued shares inthatentity or thepower todirect, or causethedirectionof,themanagementorpoliciesofthatentity,whetherthroughtheownershipofvotingsecurities,bycontractorotherwise;and;

(b) inrelationtoIntellectualProperty,possessionoftheabilitytograntthelicencesorsub-licencesasprovidedhereinwithoutviolatingthetermsofanyagreementorotherarrangementswithanyThirdParty.

“Clinical Trial Costs” means the costs incurred by ASLAN, as from the Effective Date up till the date of ASLAN’s Buy-Back Notice (as defined in Section 15.2), of carrying out clinical trials and clinical studies for the Product, such trials or studies being additional or supplementary to the Ongoing Clinical Trials as listed and defined and in Schedule 2; including, without limitation, costs of clinical research organisations, payments to clinical trial centres, and costs of Regulatory Filings.

“Clinical Trial Costs Contribution” shall be as defined in Section 5.2.

"EffectiveDate"shallmean 11^th March 2019.

"Field"shallmeanall human and animal therapeutic, diagnostic and prophylactic uses, excluding topically administered products for the treatment of keratinocyte hyperproliferative disorders and the following non-melanoma skin cancers: basal cell carcinoma, squamous cell carcinomas and Gorlin Syndrome.

“First Commercial Sale” means the first commercial sale of a Product in the relevant indication in the Field in the Territory by BIOGENETICS, or its Affiliates.  Sales for clinical study purposes, “early access programs” or similar uses shall not constitute a First Commercial Sale.  In addition, sales of a Product between BIOGENETICS and its Affiliates shall not constitute a First Commercial Sale.

“Improvement” means any improvement, development, modification or enhancement of the ASLAN Patents, the ASLAN Know-How or the Licensed Technology, whether patentable or not.

"IntellectualProperty"(or"IP")shallmeananypatents,rightstoinventions,registereddesigns,copyrightandrelatedrights,databaserights,designrights, topographyrights,trademarks,servicemarks,tradenamesanddomainnames,tradesecrets,confidentialinformation,rightsinunpatentedknow-how,andanyotherintellectualorindustrialpropertyrightsofanynatureincludingallapplications(orrightstoapply)for,andrenewalsorextensionsofsuchrightsandallsimilarorequivalentrightsorformsofprotectionwhichsubsistorwillsubsistnoworinthefutureinanypartoftheworld.

“Generic Product” means with respect to the Product, a pharmaceutical product (a) containing ASLAN003 (b) that has obtained MFDS approval in the Territory solely by means of a procedure for establishing equivalence to the Product; and (c) that is legally marketed in such country by or under authority of an entity other than BIOGENETICS or its Affiliates.

“Liabilities”meansClaims,losses,liabilities,costs,expensesordamageofanykindandhoweverarising,includinginvestigativecosts,courtcosts,legalfees,penalties,finesandinterestandamountspaidinsettlement.

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“Licence Period” shall mean the period commencing on the Effective Date and, unless terminated earlier pursuant to the terms of this Agreement, expiring on the tenth (10th) anniversary of the date of First Commercial Sale, subject to Section 11.2.

“LicensedKnow-How”meanstheASLANKnow-How,theASLANIn-LicensedKnowHowandASLAN’sinterestinanyImprovementswhicharenotpatented.

“LicensedPatents”meanstheASLANPatents, and the ASLANIn-LicensedPatents.

"LicensedTechnology"shallmean the Licensed Patents and the Licensed Know-How, including any right, title and interest in any Improvements assigned to ASLAN pursuant to Section 7.11.

“Licensing Revenue” means all gross revenue that BIOGENETICS receives from a Third Party in connection with Commercialization of the Licensed Technology.

“MaterialSafetyRisk”means,in a Party’s reasonable belief, there is an unacceptable risk a Product will cause harm in humans (according to the regulatory or ethical practices in the Territory) based upon: (i) pre-clinical safety data, including data from animal toxicology studies; or (ii) the observation of serious adverse effects in humans after that Product has been administered to or taken by humans, such as during a clinical trial or after the launch of such Product.

"MFDS" shall mean the Korean Ministry of Food and Drug Safety (formerly known as the Korea Food & Drug Administration).

"Net Sales" shall mean in respect of direct sales to Third Parties by BIOGENETICS and its Affiliates in the Territory, the gross invoice price charged from time to time by BIOGENETICS or by its Affiliates, together with all upfront payments, milestones payments, or advances, as the case may be (referred to herein as the "Selling Party"), for all Products sold or supplied by the Selling Party, in arm's length sales or supplies to Third Parties less deductions allowed to the Third Party customer by the Selling Party, to the extent actually taken by the Third Party customer, on such sales for:  

• trade, quantity, and cash discounts (including to wholesalers) consistent with usual industry practice in the Territory;

• credits, rebates and chargebacks (including those to managed-care entities and government agencies), and allowances or credits to customers on account of rejection or returns (including, but not limited to, wholesaler and retailer returns);

• freight, postage and duties, and transportation charges specifically relating to Product, including handling and insurance thereto; and

• sales (such as VAT or its equivalent) and excise taxes, other consumption taxes, customs duties and compulsory payments to governmental authorities and any other governmental charges imposed upon the sale of such Product to Third Parties;

In the event of supplies to Third Parties for non-cash or nil consideration, the gross invoice price charged from time to time by the Selling Party shall be deemed to have been charged for such supply, and prices shall be calculated and payable on the basis set out in Section 5.

Sales among the Selling Party and its Affiliates shall be excluded from the computation of Net Sales.

"NHIP" shall mean the National Health Insurance Price in the Territory for the Product as determined and approved from time to time by the relative government authorities.

“Ongoing Clinical Trials” means those clinical trials and clinical studies run by ASLAN which were completed or ongoing as at the Effective Date for the Product, as detailed in Schedule 2.

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“Party”shallmeanapartytothisAgreement.

"Product"shallmean,unlessotherwisedefined,anypharmaceuticalormedicinalitem,substance,formulationordosageforhumanusecontainingASLAN003 as an active ingredient.

“Regulatory Filings” means, with respect to Products, any preparation and/or submission to MFDS or any other regulatory body in the Territory with authority to grant marketing approvals for Products, of any regulatory application together with any material related correspondence and documentation and shall include, without limitation, any submission to a regulatory advisory board, marketing authorization application, and any supplement or amendment thereto.  For the avoidance of doubt, Regulatory Filings shall include any IND, MAA or the equivalent in the Territory.

"Territory"shallmeanthe Republic of Korea.

"ThirdParty"shallmeananyentityotherthanASLAN,BIOGENETICSoranyAffiliate ofASLANorBIOGENETICS.

“Varlitinib Agreement” means an agreement between the Parties dated 27^th February 2019 relating to the exclusive licensing in the Territory of rights in the drug known as ASLAN001 and with the generic name varlitinib.

“Varlitinib Products” means any pharmaceutical or medicinal item, substance, formulation or dosage for human use containing ASLAN001 as an active ingredient, as governed by the Varlitinib Agreement

1.2. Section,ScheduleandparagraphheadingsshallnotaffecttheinterpretationofthisAgreement.

1.3. TheSchedulesformpartofthisAgreementandshallhaveeffectasifsetoutinfullinthebodyofthisagreementandanyreferencetothisAgreementincludestheSchedules.

1.4. Unlessthecontext otherwiserequires,wordsinthesingularincludethe pluralandinthepluralincludethesingular.

1.5. Unlessthecontextotherwiserequires,areferencetoonegendershallincludeareferencetotheothergenders.

1.6. Writingorwrittenincludesfaxes.

1.7. Anywordsfollowingtheterms‘including’,‘include’,‘inparticular’oranysimilarexpressionshallbeconstruedasillustrativeandshallnotlimitthesenseofthewordsprecedingthoseterms.

1.8. A “person” includesanaturalperson,corporateor unincorporated body(whether ornothavingseparate legalpersonality), partnership,joint venture anda governmentorstatutorybodyorauthority.

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1.9. Ifawordisdefinedorphraseisdefined,itsothergrammaticalformshavethecorrespondingmeaning.

1.10. NoruleofconstructionwillapplytoaprovisiontothedisadvantageofaPartymerely becausethatPartyproposed theprovisionorwouldotherwisebenefitfromit.

2. LICENCE GRANT

2.1. Subject to the terms of this Agreement, ASLAN hereby grants to BIOGENETICS an exclusive, even as to ASLAN, license under ASLAN’s rights in the Licensed Technology to Commercialize and, if agreed in accordance with Section 4.2, manufacture Products in the Territory in the Field. To make it clear, ASLAN shall not distribute the Products nor grant to Third Party any license to Commercialize the Products in the Territory during the Licence Period of this Agreement.

2.2. All rights granted in this Agreement by ASLAN to BIOGENETICS shall be exercised in the Territory, during the Licence Period and in accordance with the terms and conditions set out in this Agreement.  

2.3. For the avoidance of doubt, ASLAN shall retain all rights to the Licensed Technology other than the commercial and (subject to Section 4.2) manufacturing rights granted to BIOGENETICS under Section 2.1.

2.4. During the Licence Period and for one (1) year thereafter, neither BIOGENETICS, nor any of its Affiliates, will conduct, participate in, or fund, directly or indirectly, either alone or with a Third Party, the development, manufacture or commercialization of a Competing Product, or conduct a drug discovery or other research program the goal of which is to identify Competing Products (“Competing Products Development”); provided however, BIOGENETICS may participate in the Competing Products Development during the Licence Period with the prior written approval of ASLAN.

2.5. None of the rights under this Agreement may be sub-licensed or sub- contracted by BIOGENETICS unless ASLAN’s prior written consent has been obtained; provided however, BIOGENETICS may assign, transfer, sub-license or sub-contract to an its Affiliates.

3. DILIGENCE

3.1. BIOGENETICS and/or its Affiliates shall use Commercially Reasonable Efforts to (i) obtain marketing approvals for Products in the Territory, and (ii) Commercialize Products in the Territory after receipt of such marketing approvals.

3.2. BIOGENETICS’s activities under Section 3.1 shall be performed by BIOGENETICS at its sole risk and responsibility, cost and expense, and in compliance with all applicable laws and regulatory requirements, including without limitation GCP, GLP and GMP. Therefore, BIOGENETICS assumes full responsibility for any loss or damage derived from the conduct and performance of this Agreement and shall be responsible for any such Claims resulting from such activities except to the extent that such loss or damage arises out of or results from, directly or indirectly, breach of any term of this Agreement, negligence, or wilful misconduct of ASLAN.

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3.3. Information and Reports.  BIOGENETICS shall keep ASLAN informed regarding the ongoing Commercialization of Products through reasonably detailed reports to be provided to ASLAN on a semi-annual basis, together with, if requested by ASLAN, face to face meetings or telephone conferences to discuss the same during ordinary business hours of BIOGENETICS.  Such semi-annual reports shall include summaries of all material activities (including regulatory activities) and results with respect to the Products in the Territory.  ASLAN shall keep BIOGENETICS informed regardingthe ongoing development status of Products including but not limited to any clinical trial studies, registration status and price information in other countries except for the Territory through reasonably detailed reports to be provided to BIOGENETICS on a semi-annual basis, together with, if requested by BIOGENETICS, face to face meetings or telephone conferences to discuss the same during ordinary business hours of ASLAN.ASLAN shall keep BIOGENETICS informed regarding the ongoing Clinical Trial Costs through a reasonably detailed report to be provided to BIOGENETICS on an annual basis.  BIOGENETICS shall have fifteen (15) days from the date of such report to review and raise any bona fide queries on the same. If ASLAN does not receive a notice of inquiries within such fifteen (15)-day period, BIOGENETICS shall be deemed to accept such report and ASLAN may thereafter submit its invoice.  BIOGENETICS shall pay the invoice within thirty (30) days in accordance with Section 5.2.  Theprovisions of Section 6 shall apply to ASLAN’s record keeping in respect of the Clinical Trial Costs and BIOGENETICS’s rights of inspection thereof, mutatis mutandis.Notwithstanding the foregoing, and for the purposes of Section 5.3:

(a) ASLAN shall promptly (and in any event within 30 days) inform  BIOGENETICS of the occurrence of FDA approval for the first indication for a Product; and

(b) BIOGENETICS shall promptly (and in any event within 30 days) inform ASLAN of the occurrence of the other events relating to Products triggering milestone payments set out in Section 5.3.

3.4. Responsibility for regulatory interactions. BIOGENETICS shall be responsible for the preparation and filing of any and all Regulatory Filings. ASLAN shall use Commercially Reasonable Efforts to provide BIOGENETICS with appropriate documents and data required, and general cooperation, to enable the dossiers and other documentation required for MFDS submissions and other Regulatory Filings to be completed.  All such Regulatory Filings will be filed in BIOGENETICS’ name and/or on its behalf. BIOGENETICS shall promptly notify ASLAN of all Regulatory Filings submitted or received by BIOGENETICS or its Affiliates with respect to Products, and upon ASLAN’s request, shall provide to ASLAN one paper copy or electronic file of all such regulatory Filings.  Additionally, BIOGENETICS will upon ASLAN’s request, to the extent reasonably required to confirm BIOGENETICS’ compliance with its obligations hereunder, provide ASLAN with reasonable additional information and data generated by or on behalf of BIOGENETICS in such semi-annual period, it being understood that ASLAN shall keep such information and data in strict confidence. Notwithstanding the foregoing, prior to any application for determination of NHIP for Products, BIOGENETICS and ASLAN shall discuss the range of target pricing to seek in such application, including a lowest acceptable price, and ASLAN’s prior approval (not to be unreasonably withheld or delayed) shall be obtained before such application is made.   Any formal acceptance by

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BIOGENETICS of a NHIPprice proposed by the relativegovernment authorities which is lower than the lowest acceptable price agreed with ASLAN beforehand, shall require prior discussionwith ASLAN and ASLAN’s prior approval, which shall not be unreasonably withheld or delayed.

3.5. The Parties shall establish procedures for the exchange and reporting of all adverse events related to the Product, which shall be governed by a Pharmacovigilance & Safety Exchange Agreement, to be entered into in due course.

4. MANUFACTURE & SUPPLY

4.1 ASLAN agrees to provide clinical drug supplies to BIOGENETICS required for Regulatory Filings by or on behalf of BIOGENETICS and for Commercialisation of Products, pursuant to a separate manufacturing and supply agreement to be negotiated in good faith by the Parties and which the Parties shall use Commercially Reasonable Efforts to enter into no later than 30^th June 2020.

4.2 Notwithstanding the foregoing, that if BIOGENETICS wishes to manufacture by itself or have manufactured by a third party the Products during the Licence Period under this Agreement, ASLAN agrees to engage in good faith discussions, using Commercially Reasonable Efforts, to negotiate and execute a manufacturing licence conferring such rights on BIOGENETICS.

5. PAYMENTS TO ASLAN

5.1 Initial Payment.  In consideration of the licenses and rights granted to BIOGENETICS hereunder, BIOGENETICS shall pay to ASLAN an initial payment of one million USD (US $1,000,000) (“the Initial Payment”), to be paid no later than thirty (30) days of ASLAN’s invoice for the same, which may be issued to BIOGENETICS any time from mutual signature of this Agreement.  The Initial Payment shall consist of (a) an upfront licence fee component, and (b) a reimbursement component, to cover ASLAN’s costs associated with the development of the Product in the Territory up to the Effective Date.  The Parties shall work in good faith to agree the relative allocation of the different components of the Initial Payment in writing as soon as possible after the Effective Date and in any event no later than 31st March 2019.  The Parties acknowledge that BIOGENETICS may be required to pay Korean withholding tax (“WHT”) at a rate of […***…] percent ([…***…] %) on all or part of the Initial Payment, depending on the agreed allocation and the WHT treatment in Korea of the different components, but that as of the Effective Date this issue has not been finally determined between the Parties.   If a suitably qualified tax expert agreeable to both Parties determines by 31st March 2019 the exact amount of WHT (if any) required to be paid by BIOGENETICS to the Korean National Tax Service, then BIOGENETICS may make payment in satisfaction of ASLAN’s invoice for the Initial Payment as above, net of such WHT, subject always to Section 5.6.

5.2 Clinical Trial Costs Contribution. BIOGENETICS agrees to reimburse ASLAN for […***…] per cent ([…***…] %) of its Clinical Trial Costs for Products designed for the treatment of acute myeloid leukemia, incurred as from the Effective Date (“the Clinical Trial Costs Contribution”).  ASLAN shall invoice BIOGENETICS for the Clinical Trial Costs Contribution on an annual basis,and, subject to Section 3.3, BIOGENETICS shall pay such invoice within thirty (30) days of receipt.

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5.3 Milestone Payments.  Upon achieving certain milestones as set out below, BIOGENETICS will make one-time milestone payments to ASLAN:

MILESTONE PAYMENTS
5.3.1 Development milestones
First Complete Response in current Phase 2 study	USD$ […***…] ([…***…] dollars)
First indication – First Commercial Sale	USD$ […***…] ([…***…] dollars)
Second indication - First Commercial Sale	USD$ […***…] ([…***…] dollars)
5.3.2 Sales milestones
Annual Net Sales in Territory exceed $[…***…] ([…***…] US dollars):	USD$ […***…] ([…***…] dollars)
Annual Net Sales in Territory exceed $[…***…] ([…***…] US dollars):	USD$ […***…] ([…***…] dollars)
Annual Net Sales in Territory exceed $[…***…] ([…***…] US dollars):	USD$ […***…] ([…***…] dollars)
Annual Net Sales in Territory exceed $[…***…] ([…***…] US dollars):	USD$ […***…] ([…***…] dollars)
Annual Net Sales in Territory exceed $[…***…] ([…***…] US dollars):	USD$ […***…] ([…***…] dollars)
Annual Net Sales in Territory exceed $[…***…] ([…***…] US dollars):	USD$ […***…] ([…***…] dollars)

     5.3.3  In relation to Section 5.3.2:

(a)  The references to “Annual Net Sales” in Section 5.3.2 shall mean the aggregate of annual Net Sales of Products covered by this Agreement plus annual Net Sales of Varlitinib Products.  As from the Effective Date of this Agreement, the Parties agree that Section 5.3 of the Varlitinib Agreement shall be deemed superseded by Section 5.3.2 above.   

(b) Where the Product is approved in different indications, Net Sales for the different indications for that drug shall be aggregated for the purposes of calculating whether Net Sales during any calendar year have reached milestones as set out above.  

5.4 Royalties. Royalties shall be paid by BIOGENETICS to ASLAN in accordance with this Section 5.4 on Net Sales of the Products in the Territory in the Field, as follows:  

For Net Sales up to the equivalent of US$[…***…] ([…***…] US dollars) during any particular calendar year:	[…***…]% ([…***…] percent) on Net Sales
For Net Sales above the equivalent of US$[…***…] ([…***…] US dollars) and up to US$[…***…] ([…***…] US dollars) during any particular calendar year	[…***…]% ([…***…] percent) on Net Sales
For Net Sales above the equivalent of US$[…***…] ([…***…] US dollars) during any particular calendar year	[…***…]% ([…***…] percent) on Net Sales

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In relation to Section 5.4:

(a)  The references to “Net Sales” shall mean the aggregate of annual Net Sales of Products covered by this Agreement plus annual Net Sales of Varlitinib Products.  As from the Effective Date of this Agreement, the Parties agree that Section 5.3A of the Varlitinib Agreement shall be deemed amended accordingly.   

(b) Where the Product is approved in different indications, Net Sales for the different indications for that drug shall be aggregated for the purposes of calculating royalties as set out above.  

5.5 Payments to ASLAN shall be on a quarterly basis and in US dollars and shall be made within thirty (30) days following the applicable calendar quarter.

5.6 Taxes. BIOGENETICS agrees to pay to ASLAN the full amount of all payments stated in this Agreement without deductions, subject to compliance with applicable laws.  For the avoidance of doubt, ASLAN shall bear ultimate liability for any tax or duties arising as a result of such payments (whether in Singapore, the Territory or otherwise). In the event that BIOGENETICS is required to withhold any taxes on amounts payable to ASLAN in accordance with applicable laws, each Party agrees to provide the other with reasonable assistance including provision of any tax forms, evidence of taxes withheld and such other information as may be reasonably necessary in order for the paying Party not to withhold tax, to withhold tax at a reduced rate under an applicable bilateral income tax treaty or for ASLAN to reclaim withheld tax.  The foregoing provisions shall apply mutatis mutandis to payments by ASLAN pursuant to Section 15.

5.7 Statement. At the time of each quarterly payment in accordance with Section 5.4, BIOGENETICS shall provide ASLAN with a statement specifying:

5.7.1the natureof andamountof thepayment received thatcontributestoLicensingRevenue(includingcopiesofanynotifications, reportsorstatementsfromanyThirdPartyrelatingtothecontribution);

5.7.2thecalculationofLicensingRevenuebasedonsuchpaymentincludingdetailsandamountofanydeductionsmadeincalculatingsuchrevenue;

5.7.3detailsofanyexchangeratesusedtoconvertanycurrencies;

5.7.4detailsoftheNetSalesfor the periodofthestatement; and

5.7.5astatementoftheamountofpaymentduetoASLANinrespectofsuchLicensingRevenue;

5.7.6uponreceiptofsuchstatement,ASLANmayissueaninvoicetoBIOGENETICSforsuchamount.Within30daysofreceiptofsuchinvoice,BIOGENETICSmustremitpaymenttoASLANtoabankaccountnominatedbyASLAN

5.7.7in respect of the fourth quarter of each calendar year, where there has been over- or under-payment to ASLAN over the previous calendar year based on the rates applicable for Net Sales in each calendar year, an explanation of any relevant adjustments (up or down) in the payment for that fourth quarter.

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5.8 Royalty Term.  Royalties payable under this Section 5 shall be paid on a Product-by-Product basis with respect to Net Sales made during the Licence Period.

5.9 Generics.   From the time that the Licensed Patents have expired and one or more Third Parties is selling a Generic Product in the Territory, then as from the next quarter year the royalty applicable under Section 5.4 shall be discounted by […***…] ([…***…]%).

5.10 Interest.  Where ASLAN does not receive payment of any sum required on or before the day on which such payment is due, BIOGENETICS shall pay ASLAN interest on the past due amount as follows: interest shall accrue thereafter on the sum due and owing to ASLAN at the lesser of seven percent (7%) over the LIBOR rate for a three month deposit in US dollars on the last Business Day of the previous calendar month, or the maximum amount allowed by law, with interest to accrue on a day to day basis without prejudice to ASLAN’s right to receive payment on the due date.

5.11 Economic Viability.  If any of the following apply:

(a) sales of Generic Products in the Territory result in an erosion of 60% or more of the price of Products in the Territory from the price at First Commercial Sale;  

(b) fluctuations in the exchange rate between the South Korean won and US dollar for a continuous period of more than two (2) months, resulting in a differential of higher than twenty per cent (20%) in comparison to the exchange rate in force on the date of signature of this Agreement; or

(c) the official Korean reimbursement price for a Product as determined from time to time by the respective governmental authority shows dramatic change (that is to say, at the end of any two month period there has been a more than 10% aggregate increase or decrease),

the Parties shall meet together either face to face or by telephone conference to discuss how to proceed, including without limitation adjusting NHIP with the consent of both Parties.

5.12 Almirall Head Licence Agreement.  BIOGENETICS will take all reasonable steps to assist ASLAN in ensuring that it complies with its obligations under the Almirall Head Licence Agreement.

6. RECORDSANDACCOUNTS

6.1. BIOGENETICS must keep complete and accurate records of all matters connected with the Commercialization of Products and must also keep proper accounts in relation to Licensing Revenue and other payments payable to ASLAN under this Agreement containing all data necessary for the calculation of the amounts payable to ASLAN pursuant to this Agreement. BIOGENETICS must keep those records and books of account for five (5) years following the end of the year to which they relate.

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6.2. Not more than once in any twelve (12) month period, BIOGENETICS must permit during business hours an independent accountant nominated by ASLAN to inspect the records and accounts maintained under Section 6.1 for the purpose of verifying their accuracy with a prior notice of ten (10) Business Days, and confirming whether all payments payable to ASLAN under this Agreement have been properly calculated and paid by BIOGENETICS.

6.3. BIOGENETICS must provide to the accountant such assistance as is reasonably required by that person in order to verify the accuracy of those records and accounts and confirm whether all payments payable to ASLAN under this Agreement have been properly calculated and paid by BIOGENETICS.

6.4. If ASLAN’s inspection reveals that any monies are outstanding then BIOGENETICS must, within 30 days after receiving notice of the amount due, pay ASLAN the outstanding amount. If the inspection reveals there was an overpayment then the amount of the overpayment may be credited against future payments due to ASLAN under this Agreement.

6.5. ASLAN shall bear the cost of the independent accountant appointed under this Section 6 except if the inspection reveals that any monies are outstanding by more than 5%, in which case BIOGENETICS must pay ASLAN’s reasonable inspection costs.

7. INTELLECTUAL PROPERTY

Patent Prosecution

7.1. ASLAN shall have the right to control the preparation, filing, prosecution and maintenance of all the ASLAN Patents.   ASLAN shall give BIOGENETICS an opportunity to review and comment on the text of each patent application for the Territory within the ASLAN Patents, as well as any other material submissions related to the ASLAN Patents in the Territory before filing, and shall supply BIOGENETICS with a copy of such patent application as filed, together with notice of its filing date and serial number. BIOGENETICS has a right to make reasonable recommendations in relation to the filing, prosecution, maintenance, enforcement and defence of the ASLAN Patents in the Territory and ASLAN shall and shall accept BIOGENETICS’s recommendations, in good faith, unless such recommendations would adversely affects the ASLAN Patents in the Territory.

7.2. BIOGENETICS shall reimburse ASLAN for the amounts paid to Third Parties by ASLAN in connection with the filing, prosecution and maintenance of the ASLAN Patents in the Territory as from the Effective Date, including without limitation, amounts paid by ASLAN as filing and maintenance fees, translation fees and amounts paid to outside patent counsel and foreign associates (“Patent Costs”).  ASLAN shall provide BIOGENETICS with an invoice for Patent Costs on a monthly basis, and payment shall be due within thirty (30) days thereafter.

7.3. If ASLAN, in its sole discretion, which discretion shall not be exercised unreasonably, decides to abandon the preparation, filing, prosecution or maintenance of any patent or patent application in the ASLAN Patents in the Territory, then ASLAN shall notify BIOGENETICS in writing thereof at least ninety (90) days prior to any due date that requires action to avoid loss of rights in connection with the applicable patent and/or patent application, and following the date of such notice BIOGENETICS shall have the

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right, at its cost, to prosecute and maintain such patents and patent applications in ASLAN’s name, provided that BIOGENETICS shall give ASLAN an opportunity to review and comment on the text of each patent application or other material submissions related to the ASLAN Patents before filing, and shall supply ASLAN with a copy of such patent application as filed, together with notice of its filing date and serial number.

Enforcement

7.4. In the event that either Party becomes aware of actual or threatened infringement of any ASLAN Patents in any country in the Territory by the manufacture or sale or use of a Product or competing product in the Field (“Infringing Product”), it shall provide the other Party with the available evidence, if any, of such infringement.

7.5. ASLAN , at its sole expense, shall have the initial right to initiate and control any enforcement of the ASLAN Patents in the Territory with respect to an Infringing Product or to defend any declaratory judgments seeking to invalidate or hold the ASLAN Patents unenforceable (each, an “Enforcement Action”), in each case in ASLAN’s own name and, if necessary for standing purposes, in the name of BIOGENETICS or its nominee and shall protect, in good faith, the interests of BIOGENETICS in taking such enforcement action.  If ASLAN does not, within one hundred twenty (120) days of receipt of notice from BIOGENETICS, take significant steps to abate the infringement or file suit to enforce the ASLAN Patents against at least one infringing party in the Territory, BIOGENETICS shall have the right to take whatever action it deems appropriate to enforce the ASLAN Patents. To make it clear of the responsibilities on the costs and expenses for the afore-mentioned enforcement action taken by BIOGENETICS, ASLAN shall fully reimburse the reasonable costs and expenses incurred to BIOGENETICS unless BIOGENETICS has breached the terms and conditions of this Agreement. The Party controlling any such enforcement action shall not settle the action or otherwise consent to an adverse judgment in such action that diminishes the rights or interests of the non-controlling Party (including in the case of BIOGENETICS, entering into any settlement admitting the invalidity of, or otherwise impairing, the ASLAN Patents) without the prior written consent of the other Party.  All monies recovered upon the final judgment or settlement of any such suit to enforce the ASLAN Patents shall be shared, after reimbursement of expenses, as follows: (i) in the event that ASLAN brought the claim, suit or action, any remaining amount shall be shared eighty percent (80%) to ASLAN, 20% to BIOGENETICS, and (ii) in the event that BIOGENETICS brought the claim, suit or action, any remaining amount shall be retained by BIOGENETICS.

7.6. In any suit to enforce and/or defend the ASLAN Patents pursuant to this Section 7, the Party not in control of such suit (a) shall, at the request and expense of the controlling Party, (b) reasonably cooperate and, to the extent possible, have its employees testify when requested and make available relevant records, papers, information, samples, specimens, and the like, and (c) further agrees to be named in and consents to join in any suit, action, or proceeding as a party to the suit, action, or proceeding to the extent necessary to establish standing in the suit, action, or proceeding.

7.7. If a Third Party asserts that a patent or other right owned by it is infringed by the manufacture, use, marketing, sale or importation of any Product, the Party becoming aware of such a matter shall immediately notify the other of it. ASLAN shall have the right to initiate, prosecute, defend and control legal action (whether by suit, proceedings, counter-claim, oppositions, customs procedure or otherwise) in respect of any such assertion. BIOGENETICS shall have the right actively to co-operate and join with ASLAN in any legal action if it (acting in good faith and reasonably) considers it necessary or desirable, and ASLAN shall have the right to have BIOGENETICS and/or its nominee joined as a passive party to any legal action if necessary, and in either

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circumstance each party shall reasonably co-operate with the other in regard to the same. All costs and expenses (including attorneys' fees) of any legal action brought in accordance with this Section 7.7, shall be borne by ASLAN, provided that where ASLAN is bearing BIOGENETICS’s costs and expenses (including attorneys' fees) if BIOGENETICS actively elects to be joined as a party to such action (as above), these shall be reasonable. Any monetary recovery in connection with legal action shall be applied first to reimburse ASLANfor its out-of-pocket costs and expenses (including management time and reasonable attorneys' fees) incurred in connection with any legal action. The remainder shall be split between the Parties in proportion to the relative degree of their active involvement in connection with the action, but if the Parties, acting in good faith, cannot agree such relative proportions, then on the basis of 50% to BIOGENETICS and 50% to ASLAN.

7.8. Patent Marking.  BIOGENETICS agrees to mark and have its Affiliates mark all patented Products they sell or distribute pursuant to this Agreement in accordance with the applicable patent statutes or regulations in the Territory.

7.9. Patent Term Extensions.  The Parties will reasonably discuss patent term adjustment, patent term extension, supplemental patent protection or related extension of rights with respect to ASLAN Patents in the Territory.  To the extent permitted by applicable law, ASLAN shall apply for and pursue any such adjustment, extension or protection as directed by BIOGENETICS, at BIOGENETICS’ cost.

7.10. ImprovementsbyASLAN.  IfanyImprovementsaremadebyASLANoritsThirdPartycollaboratorsduringtheLicence Period,thePartiesacknowledgethatASLANwillownsuchImprovementsandtheIntellectualPropertytherein. ASLAN will promptly disclose such Improvements to BIOGENETICS and they will form part of the Licensed Technology licensed hereunder.

7.11. Improvements by BIOGENETICS. All rights, title and interest in any Improvements made by or on behalf of BIOGENETICS or its Affiliates during the Licence Period shall be owned by ASLAN; and BIOGENETICS hereby assigns all of its rights, title and interest in and to such Improvements to ASLAN and agrees to do all such other acts as appropriate to allow ASLAN to perfect such rights, title and interest. BIOGENETICS will promptly disclose such BIOGENETICS Improvements to ASLAN if they are necessary or useful to the development or Commercialization of Products.

8. WARRANTIES

8.1. EachofthePartieswarrantsthat:

8.1.1 ithasfullpowerandauthoritytoenterintoandobservetheobligationsunderthisAgreementand,fortheavoidanceofdoubtASLAN warrants that the Licensed Patents and the Licensed Know-how are either owned or Controlled by it;  

8.1.2 to the best of its actual knowledge as at the Effective Date, its entry into and performance under the terms of this Agreement will not infringe the rights of any Third Party or cause it to be in breach of any obligations to a Third Party;

8.1.3 all information, data and materials provided by it to the other pursuant to this Agreement will be, to the best of its knowledge and belief, accurate and complete in all material respects.

8.2. ASLANwarrantsthat,tothebestofitsactualknowledgeasattheEffectiveDate:

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8.2.1 the exercise by BIOGENETICS of the licence rights granted to BIOGENETICS under Section 2 does not infringe the rights of any Third Party and any terms and conditions of Almirall Head Licence Agreement;

8.2.2 no Third Party has threatened or, so far as it is aware, is currently threatening proceedings in respect of infringement of any the Licensed Patents and the Licensed Know-how, and none of the same is the subject of any actual or, so far as it is aware, threatened challenge, opposition or revocation proceedings.

8.3. Anycondition,warrantyorothertermwhichisnotexpresslysetoutinthisAgreementwhichmightotherwisebeimpliedorincorporated into thisAgreement,whetherbystatute,commonlaworotherwise,is,insofarasitislawfultodoso,herebyexcluded.

8.4. CompliancewithLaw.EachPartycovenantstotheotherthatitwillcomplywithallapplicablelawsasamended,incarryingoutitsobligationspursuanttothisAgreement. Each Party covenants to the other that it and any sub-contractor legitimately appointed by it currently holds or at the relevant time will hold any and all consents, approvals, orders or authorizationsnecessarytocomplywithitsobligationsunderthisAgreement.

8.5. Disclaimers.   WithoutprejudicetoASLAN'swarrantiessetoutinSections8.1and8.2,BIOGENETICSacknowledgesthatASLANlicencestheLicensed Technology “asis”,thatis,withoutanywarrantyofanykind,expressor implied,including,withoutlimitation,warrantyofitsaccuracyorcompleteness,ofmerchantability,fitnessforaparticularpurpose(includingbutnotlimitedtomanufacturetheProductorconductthedevelopment),commercialvalue,andwithoutanywarrantyofanykind,expressorimplied,oftheinexistenceofadverseeffects,ofthesafetyorotherquality,efficiency,stability,characteristicsorusefulnessof,ormerchantability,orfitnessforaparticularpurposeofanyProduct.

9. LIABILITY

9.1. BIOGENETICSIndemnities.BIOGENETICSshallindemnify,keepindemnifiedandholdharmlessASLAN,itsAffiliatesandtheirdirectors,officersandemployees(“ASLANIndemnitees”)fromandagainstallLiabilitiesincurredinconnectionwithanyThirdPartyclaim arisingoutoforresultingfrom:

9.1.1 breach of any termof this Agreement by BIOGENETICS, or its Affiliates,contractorsorsub-licensees;

9.1.2 thenegligence,recklessnessorwilfulmisconductofBIOGENETICS,itsAffiliatesoritscontractorsorsub-licensees;

9.1.3 theCommercializationofProductsbyBIOGENETICSoritsAffiliates,sub-licenseesorcontractorsoranyend-useofsuchProductsinamannerandforapurposeauthorisedbyanyofthem,

excepttotheextentthattheLiabilitiesariseoutoforresultfrom,directlyorindirectly,breachofanytermofthisAgreement,negligence,orwilfulmisconductofanyASLANIndemnitees.

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9.2. ASLANIndemnities.ASLANshallindemnify,keepindemnifiedandholdharmlessBIOGENETICSanditsAffiliates,directors,officersandemployees(“BIOGENETICSIndemnitees”)fromandagainstallLiabilitiesincurredinconnectionwithanyThirdPartyclaimarisingoutoforresultingfrom:

9.2.1 breach of any term of this Agreement by ASLAN, or its Affiliates, contractors or sub-licensees;

9.2.2 the negligence, recklessness or wilful misconduct of ASLAN or its Affiliates or contractors in the performance of its  obligations under this Agreement,

excepttotheextentthattheLiabilitiesariseoutoforresultfrom,directlyorindirectly,breachofanytermofthisAgreement,negligence,orwilfulmisconductofanyBIOGENETICSIndemnitees.

9.3. ItisaconditionofindemnificationunderthisAgreementthat:

9.3.1 theindemnifiedPartygiveswrittennoticetotheindemnifyingPartyoftheClaiminrespectofwhichindemnificationissoughtpromptlyonbecomingawareofitanddoesnotatanytimeadmitliabilityorotherwiseattempttosettleorcompromisesuchClaimwithouttheindemnifyingParty’spriorwrittenconsent;

9.3.2 theindemnifyingPartyshall,atitscost,havesoleconductofthedefenceorcompromiseofanysuchClaimandasbetweentheindemnifyingPartyandtheindemnifiedPartyshallhavethesolerighttoanycostsanddamagesawardedasaresultofanysuchClaim;and

9.3.3 theindemnifiedPartyprovidestheindemnifyingPartysuchassistanceandco-operationasitshallreasonablyrequire,attheindemnifyingParty’sreasonablecost,inrespectoftheconductofsuchdefenceorcompromise.

9.4. Insurance.During the Licence Period, each Party, at its own expense, shall maintain product liability and other appropriate insurance or self-insure in an amount consistent with industry standards to a reasonably adequate level, and upon request each Party shall provide proof of such coverage to the other Party.

9.5. ExcludedLiabilities.SubjecttothisSection9.5,thePartiesagreethatwithrespecttoanyclaimbyonePartyagainsttheotherarisingoutoftheperformanceor failureofperformanceof theotherPartyunderthisAgreement,aPartyshallbeliabletotheotherPartyfordirectdamagesonlyandshallnotbeliableforanyindirect orconsequentiallossor damagewhatsoeverarisingunderor inrelationtotheAgreementwhetherarisingfrombreachofcontract(includingunderanyindemnity),misrepresentation(whethertortuousorstatutory),tort(includingnegligence), breach of statutory duty, strict liability including but not limited to loss of profits, loss of business, loss of goodwill or similar loss, regardless of whether arising from warranty, strict liability or otherwiseoranyotherlegaltheoryhowsoever arising, evenifthat Party wasawareofthe possibility thatsuchlossordamagemightbeincurredbytheother,exceptasaresultofaParty’swilfulmisconduct.NothinginthisSection9.5isintendedtolimitorrestricttherightsorobligationsofeitherPartyunderSection 8 [Warranties] ortolimitaParty’sliabilityinrespectofwilfulmisconduct.

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10. CONFIDENTIALITY

10.1. Confidentiality;Exceptions.InthisAgreement,“ConfidentialInformation”meansanyinformationandmaterialsdisclosedormadeavailabletoonePartybyor on behalf of the other Party in connection with thisAgreement, whether disclosedinwriting,orallyorbyanyothermeansandregardlessofthedateitwasdisclosed,excepttotheextentthatitcanbeestablishedbythereceivingPartythatsuchConfidentialInformation:

10.1.1 isinthelawfulknowledgeorpossessionofthereceivingPartypriortothetimeitwasdisclosedto,orlearnedby,thereceivingParty;

10.1.2 isdevelopedindependentlybythereceivingPartybyanemployeewithnoknowledgeofthedisclosure;

10.1.3 wasgenerallyavailabletothepublicorotherwisepartofthepublicdomainatthetimeofitsdisclosuretothereceivingParty;

10.1.4 becamegenerallyavailabletothepublicorotherwisepartofthepublicdomainafteritsdisclosureandotherthanthroughanyactoromissionofthereceivingPartyinbreachofthisAgreement;or

10.1.5 isdisclosedtothereceivingParty,otherthanunderanobligationofconfidentiality,byaThirdPartywhohasthelawfulpowertodisclosesuchinformationtothereceivingParty.

ConfidentialInformationshallbedeemedtoincludethetermsofthisAgreement.

10.2. AuthorizedUseandDisclosure. ExceptasexpresslyprovidedotherwiseinthisAgreementoronreceivingthepriorwrittenconsentoftheotherParty,eachParty:

10.2.1 must keep the Confidential Information of the other Party confidential;

10.2.2 mustnotuseanyConfidentialInformationoftheotherPartyexceptasreasonablynecessaryincarryingoutitsobligations,or exercisingitsrights,underthisAgreement(“PermittedPurpose”);

10.2.3 mayonlydiscloseanyConfidentialInformationoftheotherPartyasfollows:

(i) toitsAffiliates,directors,employees,permittedsub-licensees,consultantsandadvisors(andthedirectors, employees,consultantsandadvisorsofitsAffiliates)(“Representatives”)totheextentnecessaryforthePermittedPurposeprovidedthatthePartymustensurethatanysuchRepresentativecomplieswiththeobligationsofconfidenceandnon-usesetoutinthisAgreement;

(ii) thetermsofthisAgreementmaybedisclosedtoitslegalandfinancialadvisors,whomustbeboundbysimilarobligationsof confidentialityascontainedinthisAgreement;

(iii) if required to be disclosed to a competent authority in accordance with applicable laws, regulations or stock exchange rules (as applicable), in which case the disclosing Party shall promptly notify the other Party of such disclosure requirement to enable the other Party to seek a protective order or other form of confidential treatment for the Confidential Information, and shall thereafter disclose only that portion of the Confidential Information which is required to be disclosed in order to comply;

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(iv) withASLAN’spriorwrittenconsent(nottobeunreasonablywithheld),BIOGENETICSmaydiscloseASLAN’sConfidentialInformation to potential investors,or acquirers, on a need toknowbasis,andwhomustbeboundbysimilarobligationsofconfidentialityascontainedinthisAgreement;

(v) BIOGENETICSmaydisclose IP of ASLANtotheextentsuchdisclosureisreasonablynecessaryinprosecutingordefendinglitigation, or conductingpreclinicalorclinicaltrials.

10.3. Termofconfidentiality.TheobligationsofconfidentialitysetoutinthisSection 10applyfrom the Effective Date until five (5) years after the expiration or termination of this Agreement.

10.4. Specificenforcement.EachPartyacknowledgesthat:

10.4.1 thevalueoftheotherParty’sConfidentialInformation,whichincludesanyjointlyownedConfidentialInformation,isuniqueanddifficulttoassessinmonetaryterms;

10.4.2 a breach by it of any of its obligations of confidentiality under this Agreement may irreparably harm the Party disclosing such Confidential Information, and damages may not be an adequate remedy for any such breach; and

10.4.3 therefore, if it actually breaches or threatens to breach the confidentiality obligations set forth in this Agreement, the Party whose Confidential Information is the subject of such breach, or who is affected by such breach, may seektoenforcethisAgreementbywayofinjunctiverelieforspecificperformanceasaremedy(inadditiontoanyotheravailablerelief)withoutproofofactualorspecial damage.

10.5. Publications.  ASLAN and BIOGENETICS agree not to issue any press releases or public announcements concerning the terms of this Agreement if the other Party (or its Affiliates or products) is named therein (directly or by referencing items such as logotypes, corporate image, commercial brands, or trademarks) or such release or announcement discloses Confidential Information of the other Party or discloses information which will or may (assessed reasonably) cause harm to the commercial value or reputation of the other’s products containing ASLAN003 (and to ensure that their respective Affiliates do not do so) without the prior written consent of the other Party, subject to Section 10.2.3 (iii).  The Party interested in issuing the publication shall submit the proposal to the other Party, who shall have at least seven (7) Business Days for review, except as required by a governmental authority and applicable Law, including disclosure required by any securities exchange; provided that following agreement upon the content of such disclosure, subsequent releases which do not materially depart from such agreed content may be made without prior written consent from the other Party.

11. TERM AND TERMINATION

11.1. Term.ThisAgreement shall become effectiveasoftheEffectiveDateand, unless earlier terminated under this Agreement, shall continue in full force and effect until the expiry of the Licence Period, subject to Section 11.2.

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11.2. Automatic Renewal For One Further Year.  If either Party wishes this Agreement to expire without automatic renewal for a further year, then it must serve notice on the other to that effect at least ninety (90) days before expiry of the Licence Period.  In the absence of such notice, then this Agreement shall automatically renew for one (1) further year at which point it shall definitively expire unless the Parties mutually agree in writing otherwise.

11.3. TerminationForBreach.EitherPartymayterminatethisAgreementintheeventtheotherPartyshallhavebreachedordefaultedintheperformanceofanyofitsmaterialobligationshereunder,andsuchdefaultshallhavecontinued forninety(90)daysafterwrittennoticethereofwasprovidedtothebreachingPartybythenon-breachingParty.Anyterminationshallbecomeeffectiveattheendofsuchninety(90)dayperiodunlessthebreachingParty(oranyotherPartyonitsbehalf)hascuredanysuchbreachordefaultprior to the expiration oftheninety(90)dayperiod.

11.4. Termination For Material Safety Risk.EitherPartymayterminatetheAgreementatanytimeintheeventofaMaterialSafetyRiskassociatedwiththeProduct.

11.5. Termination on Insolvency.  Either Party may terminate this Agreement by notice,if,atany time, theotherParty(i)suspendspayment ofitsdebtsorisunabletopayits debtsasthey falldueoradmits inabilitytopayitsdebtsorisdeemedunabletopayitsdebts or (ii)apetitionisfiled,anoticeisgiven,aresolutionispassed,oranorderismade,fororinconnectionwith the winding upofthatParty(otherthanforthesolepurposeofaschemeforasolventamalgamationofthatPartywithoneormoreothercompaniesorthesolventreorganisationofthatParty);or(iii)anapplicationismadetocourt,oranorderismade,fortheappointmentofanadministrator,orifanadministratorisappointedoverthatParty;or(iv)areceiverisappointedoveralloranyoftheassetsofthatParty;or(v)anysimilarinsolvencyeventtoanyoftheforegoingoccursinanyjurisdiction;or(vi)thatPartysuspendsorceases,orthreatenstosuspendorcease,tocarryonallorasubstantialpartofitsbusiness.

12. EFFECT OF TERMINATION.

12.1. AccruedRights,SurvivingObligations.TerminationorexpirationoftheAgreementforanyreasonshallbewithoutprejudicetoanyobligationswhichshallhaveaccruedpriortosuchterminationorexpiration,including,withoutlimitation,anyandalldamagesarisingfromanybreachhereunder.

12.2. Upon any termination of the Agreement, the licence granted to BIOGENETICS in Section 2.1 shall terminate, except and only for long as needed by BIOGENETICS to meet its obligations under this Section 12.

12.3. Upon any termination of the Agreement for any reason:

a) BIOGENETICS shall promptly assign and transfer to ASLAN all Regulatory Filings with respect to Products in the Territory that are held or Controlled by or under authority of BIOGENETICS or its Affiliates (including Regulatory Filings obtained by permitted sub-licensees to the extent such sub-licensees’ sublicense(s) do not survive the

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termination of this Agreement), and shall take such actions and execute such other instruments, assignments and documents as may be necessary to effect the transfer of rights under such Regulatory Filings to ASLAN.  BIOGENETICS shall cause each of its Affiliates and all such sub-licensees whose sublicense(s) do not survive the termination of this Agreement to transfer any such Regulatory Filings to ASLAN if this Agreement terminates.  If applicable laws, rules or regulations prevent or delay the transfer of ownership of a Regulatory Filing to ASLAN, BIOGENETICS shall grant, and does hereby grant, to ASLAN an exclusive and irrevocable right of access and reference to such Regulatory Filing for the Product(s), and shall cooperate fully to make the benefits of such Regulatory Filings available to ASLAN and/or its designee(s).  Within ninety(90) days after notice of such termination, BIOGENETICS shall provide to ASLAN copies of all such Regulatory Filings, and of all preclinical and clinical data (including raw data, original records, investigator reports, both preliminary and final, statistical analyses, expert opinions and reports, safety and other electronic databases) and other Know-How information pertaining to the Product, or the manufacture thereof.  ASLAN shall be free to use and disclose such Regulatory Filings and other items in connection with the exercise of its rights and licences under this Section 12.3.

b) BIOGENETICS shall grant, and hereby does grant, effective upon the effective date of such termination: (i) an exclusive, worldwide, irrevocable, fully paid-up licence to ASLAN to make, use, sell, offer for sale or import Product(s), under any patent rights owned or Controlled by BIOGENETICS or its Affiliates that: (A) were generated by BIOGENETICS or its Affiliates in connection with the Development or Commercialization of the Product(s) prior to the effective date of such termination, or (B) were otherwise utilized by BIOGENETICS, its Affiliates or permitted sub-licensees in the Development or Commercialization of the Product(s); and (ii) a non-exclusive, worldwide, fully-paid licence to ASLAN under any know-How that: (A) were generated by BIOGENETICS or, its Affiliates in connection with the development or Commercialization of the Product(s) prior to the effective date of such termination, or (B) were otherwise utilized by BIOGENETICS, its Affiliates or such sub-licensees in the development or Commercialization of the Product(s), in case under the preceding sub-clauses (i) and (ii) solely to the extent reasonably necessary for ASLAN to make, use, sell, offer for sale or import Product(s) in the Field; provided, however, if any such patent rights or other Intellectual Property licensed to ASLAN hereunder is subject to payment obligations to a Third Party, BIOGENETICS shall promptly disclose such obligations to ASLAN in writing and such patent rights or other Intellectual Property shall be deemed to be Controlled by BIOGENETICS only if ASLAN agrees in writing to reimburse all amounts owed to such Third Party as a result of ASLAN’s exercise of such licence.

c) BIOGENETICS shall cause to be assigned, and hereby does assign, to ASLAN all rights in and to any and all trademarks used in connection with the Commercialization of the Product by BIOGENETICS or its Affiliates.  It is understood that such assignment shall not include the name or trademark for BIOGENETICS’ company itself.

d) If there are any ongoing clinical trials with respect to the Product being conducted by or on behalf of BIOGENETICS, its Affiliates at the time of notice of termination,

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BIOGENETICS agrees to (i) promptly transition to ASLAN or its designee all of such clinical trials and the activities related to or (ii) terminate such clinical trials; in each case as requested by ASLAN and subject to compliance with applicable laws, rules and regulations.

12.4. For a) through d) in Section 12.3 above, ASLAN shall be responsible for the reasonable costs of such transition except in the case of a termination of this Agreement by ASLAN pursuant to Section 11.3 or 11.5, in which case BIOGENETICS shall be responsible for such costs.

12.5. (a) If requested by ASLAN, BIOGENETICS or its Affiliates shall continue to distribute and sell the Products in the Territory, in accordance with the terms and conditions of this Agreement, for a period requested by ASLAN not to exceed six (6) months following the effective date of termination (“Commercialization Wind-Down Period”) provided that ASLAN may terminate this Commercialization Wind-Down Period upon thirty (30) days’ notice to BIOGENETICS.  Notwithstanding any other provision of this Agreement, during this Commercialization Wind-Down Period, BIOGENETICS’ and its Affiliates’ rights with respect to the Products (including the licences granted under Section 2.1) shall be non-exclusive, and ASLAN shall have the right to engage one or more other partner(s) or distributor(s) of the Products in all or part of the Territory.  The Products sold or disposed by BIOGENETICS or its Affiliates during this Commercialization Wind-Down Period shall be subject to royalties under Section 5.4 above.  After the Commercialization Wind-Down Period, BIOGENETICS, and its Affiliates shall not sell the Products or make any representation that, or implying that, they are a continuing licensee of or distributor for ASLAN for the Products.

(b) If ASLAN wishes BIOGENETICS or its Affiliates terminate to distribute and sell the Products in the Territory without the Wind-Down Period mentioned above, ASLAN or its designee(s) shall purchase all quantities of the Product in BIOGENETICS’ or its Affiliates’ inventory at the price BIOGENETICS actually incurred to purchase the quantities so provided to ASLAN within thirty (30) days after the effective date of termination.

12.6. BIOGENETICS agrees to fully cooperate with ASLAN and its designee(s) to facilitate a smooth, orderly and prompt transition of the development and Commercialization of Products to ASLAN and/or its designee(s) during the Commercialization Wind-Down Period.  Without limiting the foregoing BIOGENETICS shall, subject to applicable date privacy laws and its relevant contractual confidentiality obligations to Third Parties, promptly provide ASLAN (i) copies of customer lists, customer data and other customer information relating to the Products and (ii) (if applicable) manufacturing information (including protocols for the production, packaging, testing and other manufacturing activities) relating to the Product in BIOGENETICS’ Control, which in each case ASLAN shall have the right to use and disclose for any purpose during this Commercialization Wind-Down Period and thereafter.  Upon request by ASLAN, BIOGENETICS shall transfer to ASLAN all quantities of the Product in its or its Affiliates’ Control (as requested by ASLAN), within thirty (30) days after the end of this Commercialization Wind-Down Period; provided, however, that ASLAN shall reimburse BIOGENETICS for the costs that BIOGENETICS actually incurred to manufacture or purchase the quantities so provided

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to ASLAN, which in the case BIOGENETICS has manufactured such quantities of Product itself, shall be BIOGENETICS’ fully-burdened manufacturing cost.  If any Product was manufactured by any Third Party for BIOGENETICS, or BIOGENETICS had contracts with vendors which contracts are necessary or reasonably useful for ASLAN to take over responsibility for the Product in the Territory, then BIOGENETICS shall cooperateto the extent reasonably possible and requested in writing by ASLAN, to assign all of the relevant Third-Party contracts to ASLAN, and in any case, BIOGENETICS agrees to cooperate with ASLAN to ensure uninterrupted supply of the Products.  ASLANshall be responsible for the reasonable costs of such assignment except in the case of a termination of this Agreement by ASLANpursuant to Section 11.3or 11.5, in which case BIOGENETICSshall be responsible for such costs.  If BIOGENETICS or its Affiliatemanufactured any Product at the time of termination, then BIOGENETICS (or its Affiliate) shall continue to provide for manufacturing of such Product for ASLAN, at  its fully-burdened manufacturing costs therefor, from the date of notice of such termination until such time as ASLAN is able, using diligent efforts to do so but no longer than the expiration of the Commercialization Wind-Down Period, to secure an acceptable alternative commercial manufacturing source from which sufficient quantities of the Product may be procured and legally sold in the Territory.

12.7. Survival.  Sections 5, 6, 7.11, 9, 10, 12 and 13.11 of this Agreement shall survive expiration or termination of this Agreement for any reason.  With respect to any termination or expiration of this Agreement, all rights and obligations of the Parties under this Agreement shall terminate upon such expiration or termination, except to the extent otherwise provided in this Article 12.  

12.8. Termination is not the sole remedy under this Agreement and, whether or not termination is effected, all other remedies will remain available except as agreed to otherwise herein.

13. GENERAL

13.1. Assignment.ThisAgreementshallnotbeassignablebyeitherPartytoanyThirdPartyheretowithoutthewrittenconsentoftheotherPartyhereto,nottobeunreasonablywithheldordelayed except to the extent provided in Section 2.5 under this Agreement.IfanypermittedassignmentwouldresultinwithholdingorothersimilartaxesbecomingdueonpaymentsfromtheassigningPartytotheotherPartyunderthisAgreement,theassigningPartyshallberesponsibleforallsuchtaxesresultingfromsuchassignment,andtheamountofsuchtaxesshallnotbewithheldorotherwisedeductedfromanyamountspayabletootherParty.Noassignmentandtransfershallbevalidandeffectiveunlessanduntiltheassignee/transferee agreesinwriting tobeboundbythe provisionsofthisAgreement.ThetermsandconditionsshallbebindingonandinuretothebenefitofthepermittedsuccessorsandassignsoftheParties.

13.2. Independent status of the Parties. The Parties to this Agreement are independent contractors and agree that the relationship between the Parties shall not constitute a partnership, joint venture or agency. No Party shall have the authority to make any statement, representation or commitment of any kind, or to take any action, which shall be binding on the other Party, without the prior written consent of the other Party.

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13.3. Waiver. No delay or omission by a Party in exercising or availing itself of any right, power or privilege hereunder shall preclude the later exercise of any such right, power or privilege by such Party. No waiver shall be effective unless made in writing with specific reference to the relevant provision(s) of this Agreement and signed by a duly authorized representative of the Party granting the waiver. Waiver by a Party of a breach hereunder by the other Party shall not be construed as a waiver of any succeeding breach of the same or any other provision.

13.4. Force majeure. Neither Party shall be deemed to be in breach of this Agreement or otherwise liable to the other by reasons of any delay in performance or non-performance of any of its obligations under this Agreement, to the extent that such delay or non-performance is due to any event of force majeure, including without limitation any wars, insurrections, strikes, acts of God, Governmental actions or controls or any other contingency beyond its control. The Party whose performance of obligations has been delayed by force majeure shall use its best efforts to overcome the effect of the force majeure event as soon as possible. The Party affected by the force majeure shall notify immediately to the other Party the existence of the force majeure. The other Party shall have no right to demand indemnity or damages as a result of the force majeure event. If the event of force majeure preventing performance continues for more than six (6) months from the date of notice given pursuant thereto and such suspension of performance would otherwise constitute a material breach under this Agreement, the non-force majeure Party may terminate this Agreement, by giving written notice of termination to the other without liability to any of the Parties, except the obligation to make any payments due up to such date under this Agreement. Termination under this Section 13.4 shall be considered as termination under Section 11.3 provided that no Party shall be entitled to damages or any other legal remedy in connection therewith.

13.5. Entire Agreement. This Agreement embodies all of the understandings and obligations between the Parties with respect to the subject matter hereof, and supersedes, replaces and cancels all prior agreements or understandings between the Parties with respect to the same.   

13.6. Amendments. No amendments to this Agreement shall be valid unless executed in writing duly authorized signatories of both Parties.  

13.7. Notices. All notices, instructions and other communications hereunder or in connection herewith shall be in writing, shall be sent to the address of the relevant Party set forth below and shall be (a) delivered personally, (b) sent via a reputable international overnight courier service, or (c) sent by facsimile transmission with confirmation by overnight courier. Any such notice, instruction or communication shall be deemed to be delivered by the sending Party in the case of (a) actual receipt, (b) signature of the receipt by the receiving Party and (c) issuance of electronic confirmation of receipt, if transmitted by facsimile (if such transmission is on a Business Day, or otherwise, on the next Business Day following such transmission). Either Party may change its address by giving notice to the other Party in the manner provided above. All notices shall be in English language. Additionally, all information, documents and reports which ASLAN is required to provide or send to BIOGENETICS under this Agreement, and which are not originally in English, shall be sent together with their applicable translation into English.

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(a)If to ASLAN:

ASLAN Pharmaceuticals Pte Limited

83 Clemenceau Avenue

#12-03 UE Square

Singapore 239920

Attention: General Counsel

Fax No.: +65 6225 2419

(b)If to BIOGENETICS:

BIOGENETICS CO., LTD

11^th Liveplex Tower,

702 Eonju-ro,

Seoul,

Republic of Korea

Attention: Joohoon Ahn / CEO

Fax No.: + 82 2 2622 7799

13.8. Severability. In the event any portion of this Agreement shall be held illegal, void or ineffective, the remaining portion hereof shall remain in full force and effect and shall not be affected. If any of the terms or provisions of this Agreement are in conflict with any applicable statute or rule of law, then such terms or provisions shall be deemed inoperative to the extent they may conflict therewith and shall be deemed to be modified to conform to such statute or rule of law. However, in case such invalidation or unenforceability injures the rights and interests of either Party, the Parties hereto shall renegotiate the corresponding provisions of this Agreement in good faith.

13.9. Third-Party beneficiaries. None of the provisions of this Agreement shall be for the benefit of or enforceable by any Third Party including, without limitation, any creditor of any Party hereto. No such Third Party shall obtain any right under any provision of this Agreement or shall by reason of any such provision make any claim in respect of any debt, liability or obligation (or otherwise) against any Party hereto.

13.10. Governing Law.  This Agreement and any dispute arising from the performance or breach hereof shall be governed, construed and enforced in accordance with the laws of Singapore, without regard or giving effect to the conflicts of law principles thereof. The Parties expressly exclude application of the United Nations Convention for the International Sale of Goods.

13.11. Dispute Resolution.

(a) Internal Resolution. Except as otherwise expressly provided herein, in the event of any controversy, claim or other dispute arising out of or relating to any provision of this Agreement or the interpretation, enforceability, performance, breach, termination or validity hereof (a “Dispute”), such Dispute shall be first referred to the Chief Executive Officer (CEO) of each Party or the Person that each of them may delegate (such delegate being a senior director or above), for resolution, prior to proceeding under the following provisions of this Section. For the avoidance of doubt, this internal resolution proceeding shall not and cannot be used by any of the Parties as a way to

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modify the rights and obligations under the Agreement or as a way to modify the agreements already reached by the Parties as they have been reflected in the Agreement. Any Parties’ resolution under this proceeding shall be resolved in accordance with the terms and conditions of the Agreement and the rights and obligations of the Parties as they are currently reflected in the Agreement. This internal resolution proceeding will be used as the last resort for the Parties to avoid to enter into a dispute to be resolved by the arbitration proceeding below. A Dispute shall be referred to such executives upon any Party providing the other Party with written notice that such Dispute exists, and such executives, or their designees, shall attempt to resolve such Dispute through good faith discussions, each Party acting reasonably, within sixty (60) Business Days of being referred to such executives.  

(b) Arbitration. Except as otherwise agreed in writing, the Parties agree that any Dispute over any matter which has not been resolved following the procedures set out in Section 13.11(a) must be finally resolved through a binding arbitration which the Parties agree to accept in lieu of litigation or other legally available remedies (except for injunctive relief where such relief is necessary to protect a Party from irreparable harm pending the outcome of the arbitration). Any such arbitration shall be settled in Hong Kong International Arbitration Centre (“HKIAC”) in accordance with its Rules of Arbitration by one (1) arbitrator chosen in accordance with said Rules. The arbitration shall be conducted in English and will be held in Hong Kong. The award rendered by HKIAC shall be binding and final upon the Parties.

13.12. Use of Name. None of the Parties is entitled to use the corporate or commercial name of the other Party, for any advertisement or promotional purposes without the prior written consent of the other Party.

13.13. Awareness.  In this Agreement when a Party's liability for a statement is limited by the extent of its 'awareness', this shall be construed to mean a level of awareness assuming reasonable enquiries have been made.

13.14. Counterparts.ThisAgreementmaybeexecutedintwoormorecounterparts,eachofwhichshallbedeemedanoriginal,butallofwhichtogethershallconstituteoneandthesameinstrument.

14. NEW COMMERCIAL ENTITY

14.1. The Parties acknowledge that ASLAN and BIOGENETICS may wish in the future to establish a new commercial entity (the “Commercial JV Co”) intended to promote the introduction and Commercialization of oncology drugs in the Territory.

14.2. If the Commercial JV Co is established, the financial and other terms and conditions set out in this Agreement shall be reviewed and discussed by both parties and revised as mutually agreed. However the Parties agree to negotiate in principle that:

(a) BIOGENETICS shall own a majority stake in the Commercial JV Co;

(b) ASLAN shall own a minority stake in the Commercial JV Co but shall have board representation; and

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(c) ASLAN shall have a right (but not the obligation) to co-invest at each funding round for the Commercial JV Co at a valuation per share (to be negotiated among ASLAN, BIOGENETICS and where relevant, other investors) applying to other new investors in the Commercial JV in each funding round.

14.3. Prior to establishing the Commercial JV, ASLAN and BIOGENETICS shall enter into a separate definitive agreement setting forth among others, the ownership structure described in Section 14.2 above, the rights and obligations of ASLAN and BIOGENETICS and other terms.

15. BUY-BACK OPTION

15.1. ASLAN reserves the right any time between the Effective Date and the date of first submission of an NDA to the MFDS for Products in the Territory, to revoke the rights granted to BIOGENETICS pursuant to this Agreement without any liability, subject to ASLAN complying with the terms set out below ("Buy-Back Option").

15.2. ASLAN may exercise the Buy-Back Option by giving thirty (30) days' written notice (or such shorter period as the Parties may agree) to this effect ("Buy-Back Notice") to BIOGENETICS.  The Buy-Back Notice shall specify: (i) the effective date of the revocation effected by the Buy-Back Option, and (ii) the amount to be paid by ASLAN to BIOGENETICS in accordance with Sections 15.3 or 15.4 (as applicable).

15.3. In the event ASLAN has agreed detailed terms with a Third Party for a major international licensing deal for ASLAN003, in respect of which the territories covered by the licence include at least the USA, the European Union and either or both of China or Japan) (“Global Deal”), then once the Buy-Back Option has been exercised and the Global Deal has been entered into, ASLAN shall pay to BIOGENETICS the following sums:

(a) a sum equal to the Total Amount Paid multiplied by a factor of one point two (1.2), the resulting amount payable within thirty (30) days of the BIOGENETICS’s invoice for the same; and the “Total Amount Paid” shall mean the aggregate of: accumulated Clinical Trial Costs Contributions, plus the Initial Payment pursuant to Section 5.1, plus milestones paid pursuant to Section 5.3, all as actually paid by BIOGENETICS and received by ASLAN, plus sums actually paid by BIOGENETICS in relation to Regulatory Filings, all as shall have occurred between the Effective Date and the date of the Buy-Back Notice; and

(b) a sum equal to two per cent (2%) of the upfront payment actually received by ASLAN from the Global Deal (“the Share of Upfront”). ASLAN undertakes to inform BIOGENETICS within thirty (30) days of receipt of such upfront payment that it has received the same, providing adequate details for the purposes of this Section, and, upon receiving BIOGENETICS’s correct invoice for the Share of Upfront, to pay the Share of Upfront to BIOGENETICS within thirty (30) days; and

(c) thereafter, two per cent (2%) of all royalties and sales milestones actually received by ASLAN from the Global Deal.

15.4. In the absence of ASLAN agreeing the detailed terms of a Global Deal with a Third Party, then once the Buy-Back Option has been exercised ASLAN shall pay to BIOGENETICS the following sum:  

(a) a sum equal to the Total Amount Paid (as defined in Section 15.3(a)) multiplied by a factor of one point five (1.5), the resulting amount payable within thirty (30) days of the BIOGENETICS’s invoice for the same.

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15.5. Upon exercise by ASLAN of the Buy-Back Option in accordance with Section 15.2, and subject to any Commercialization arrangements with Third Parties entered into with ASLAN's consent and approval: (i) all licences granted to BIOGENETICS under Section 2 shall cease; (ii) BIOGENETICS shall cease all exploitation of the Licensed Technology; (iii) BIOGENETICS shall promptly return to ASLAN, at ASLAN's expense or, if ASLAN so elects, permanently delete, all records and copies (including electronic copies) of the Licensed Technology, of technical material in its possession relating to the Products, and of any information (whether or not technical) of a confidential nature communicated to it by ASLAN, either in contemplation or as a result of this Agreement; and (iv) within ninety (90) days after the date of revocation specified in the Buy-Back Notice BIOGENETICS shall promptly destroy or, if ASLAN shall so elect, deliver to ASLAN or any other person designated by ASLAN, at ASLAN's expense, all Product(s) that BIOGENETICS has not disposed of within 90 days after the date of termination.  BIOGENETICS agrees (at ASLAN's cost) to execute such documents and do all such acts and things as ASLAN may deem desirable or necessary pursuant to its exercise of its rights under this Section 15.5.

IN WITNESS WHEREOF,thePartieshaveexecutedthisAgreementinduplicateoriginalsbytheirdulyauthorizedrepresentativesasofthedateandyearfirstabovewritten.

EachpersonexecutingthisAgreementonbehalfofaPartyrepresentsandwarrantshis/hercapacityandauthoritytodoso.

ASLAN PHARMACEUTICALS PTE LTD		BIOGENETICS CO., LTD
By:	/s/ Carl Firth	By:	/s/ Joohoon Ahn
Name:	Carl Firth	Name:	Joohoon Ahn
Title:	CEO	Title:	CEO
Date:11th March 2019		Date:11th March 2019

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Schedule 1

[…***…]

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Schedule 2

[…***…]

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