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CONDENSED CONSOLIDATED STATEMENTS OF STOCKHOLDERS' EQUITY - USD ($)
$ in Thousands
Common Stock
Additional Paid-In Capital
Accumulated Other Comprehensive Income
Accumulated Deficit
Total
Balances at beginning of period at Dec. 31, 2020 $ 3 $ 392,322 $ 13 $ (81,724) $ 310,614
Balances at beginning of period (in shares) at Dec. 31, 2020 34,383,719        
Increase (Decrease) in Stockholders' Equity [Roll Forward]          
Issuance of common stock upon exercise of stock options   225     225
Issuance of common stock upon exercise of stock options (in shares) 62,197        
Vesting of restricted common stock from early-exercised stock options   21     21
Stock-based compensation expense   2,000     2,000
Net loss       (16,086) (16,086)
Unrealized gain (loss) on marketable securities     28   28
Balances at end of period at Mar. 31, 2021 $ 3 394,568 41 (97,810) 296,802
Balances at end of period (in shares) at Mar. 31, 2021 34,445,916        
Balances at beginning of period at Dec. 31, 2020 $ 3 392,322 13 (81,724) 310,614
Balances at beginning of period (in shares) at Dec. 31, 2020 34,383,719        
Increase (Decrease) in Stockholders' Equity [Roll Forward]          
Net loss         (61,732)
Unrealized gain (loss) on marketable securities         (26)
Balances at end of period at Sep. 30, 2021 $ 3 399,690 (13) (143,456) 256,224
Balances at end of period (in shares) at Sep. 30, 2021 34,492,507        
Balances at beginning of period at Mar. 31, 2021 $ 3 394,568 41 (97,810) 296,802
Balances at beginning of period (in shares) at Mar. 31, 2021 34,445,916        
Increase (Decrease) in Stockholders' Equity [Roll Forward]          
Issuance of common stock upon exercise of stock options   28     28
Issuance of common stock upon exercise of stock options (in shares) 7,323        
Vesting of restricted common stock from early-exercised stock options   5     5
Stock-based compensation expense   2,456     2,456
Net loss       (22,740) (22,740)
Unrealized gain (loss) on marketable securities     (23)   (23)
Balances at end of period at Jun. 30, 2021 $ 3 397,057 18 (120,550) 276,528
Balances at end of period (in shares) at Jun. 30, 2021 34,453,239        
Increase (Decrease) in Stockholders' Equity [Roll Forward]          
Issuance of common stock upon exercise of stock options   140     140
Issuance of common stock upon exercise of stock options (in shares) 39,268        
Vesting of restricted common stock from early-exercised stock options and sales of restricted common stock   5     5
Stock-based compensation expense   2,488     2,488
Net loss       (22,906) (22,906)
Unrealized gain (loss) on marketable securities     (31)   (31)
Balances at end of period at Sep. 30, 2021 $ 3 399,690 (13) (143,456) 256,224
Balances at end of period (in shares) at Sep. 30, 2021 34,492,507        
Balances at beginning of period at Dec. 31, 2021 $ 3 402,244 (202) (168,395) 233,650
Balances at beginning of period (in shares) at Dec. 31, 2021 34,498,443        
Increase (Decrease) in Stockholders' Equity [Roll Forward]          
Issuance of common stock upon exercise of stock options   220     220
Issuance of common stock upon exercise of stock options (in shares) 107,060        
Vesting of restricted common stock from early-exercised stock options   4     4
Stock-based compensation expense   2,626     2,626
Net loss       (26,983) (26,983)
Unrealized gain (loss) on marketable securities     (533)   (533)
Balances at end of period at Mar. 31, 2022 $ 3 405,094 (735) (195,378) 208,984
Balances at end of period (in shares) at Mar. 31, 2022 34,605,503        
Balances at beginning of period at Dec. 31, 2021 $ 3 402,244 (202) (168,395) 233,650
Balances at beginning of period (in shares) at Dec. 31, 2021 34,498,443        
Increase (Decrease) in Stockholders' Equity [Roll Forward]          
Net loss         (67,653)
Unrealized gain (loss) on marketable securities         (540)
Balances at end of period at Sep. 30, 2022 $ 4 417,624 (742) (236,048) 180,838
Balances at end of period (in shares) at Sep. 30, 2022 36,932,597        
Balances at beginning of period at Mar. 31, 2022 $ 3 405,094 (735) (195,378) 208,984
Balances at beginning of period (in shares) at Mar. 31, 2022 34,605,503        
Increase (Decrease) in Stockholders' Equity [Roll Forward]          
Issuance of common stock upon exercise of stock options   21     21
Issuance of common stock upon exercise of stock options (in shares) 21,095        
Vesting of restricted common stock from early-exercised stock options   4     4
Stock-based compensation expense   2,759     2,759
Issuance of common stock from at the market offering, net of issuance costs of $0.3 million $ 1 7,188     7,189
Issuance of common stock from at the market offering, net of issuance costs of $0.3 million (in shares) 2,272,727        
Net loss       (20,831) (20,831)
Unrealized gain (loss) on marketable securities     (176)   (176)
Balances at end of period at Jun. 30, 2022 $ 4 415,066 (911) (216,209) 197,950
Balances at end of period (in shares) at Jun. 30, 2022 36,899,325        
Increase (Decrease) in Stockholders' Equity [Roll Forward]          
Issuance of common stock upon exercise of stock options   56     56
Issuance of common stock upon exercise of stock options (in shares) 33,272        
Vesting of restricted common stock from early-exercised stock options   3     3
Stock-based compensation expense   2,499     2,499
Net loss       (19,839) (19,839)
Unrealized gain (loss) on marketable securities     169   169
Balances at end of period at Sep. 30, 2022 $ 4 $ 417,624 $ (742) $ (236,048) $ 180,838
Balances at end of period (in shares) at Sep. 30, 2022 36,932,597