Stock-Based Compensation (Tables)

9 Months Ended

Sep. 30, 2022

Stock-Based Compensation

Schedule of stock option activity

		Weighted‑		Weighted‑
		Average		Average	Aggregate
	Number of	Exercise		Contractual	Intrinsic
	Shares	Price		Term (in years)	Value (in thousands)
Outstanding as of December 31, 2021	4,392,836	$	11.71	8.3	$	6,801
Granted	1,885,975	$	5.44
Exercised	(161,427)	$	1.84
Forfeited and cancelled	(404,117)	$	12.43
Outstanding as of September 30, 2022	5,713,267	$	9.89	8.2	$	5,408
Vested and expected to vest as of September 30, 2022	5,713,267	$	9.89	8.2	$	5,408
Options exercisable as of September 30, 2022	2,130,324	$	10.79	7.3	$	2,500

Schedule of unvested common stock from option early exercises

	Shares
Unvested restricted common stock as of December 31, 2021	14,070
Vested	(9,927)
Unvested restricted common stock as of September 30, 2022	4,143

Schedule of restricted common stock award activity

		Weighted‑
		Average
		Grant‑Date
	Shares	Fair Value
Unvested restricted common stock as of December 31, 2021	770	$	0.85
Vested	(770)		0.85
Unvested restricted common stock as of September 30, 2022	—	$	—

Schedule of stock based compensation expense

The Company recorded stock-based compensation expense in the following expense categories of its consolidated statements of operations and comprehensive loss (in thousands):

	Three Months Ended					Nine Months Ended
	September 30,					September 30,
	2022		2021		2022		2021
Research and development expenses	$	1,041	$	1,031	$	3,151	$	3,216
General and administrative expenses		1,458		1,457		4,733		3,728
	$	2,499	$	2,488	$	7,884	$	6,944