X0306 4 2020-06-30 0 0001722271 Akouos, Inc. AKUS 0001674324 5AM Ventures V, L.P. 501 2ND STREET, SUITE 350 SAN FRANCISCO CA 94107 0 0 1 0 0001791889 5AM Partners V, LLC 501 2ND STREET, SUITE 350 SAN FRANCISCO CA 94107 0 0 1 0 0001753000 5AM Opportunities I, L.P. 501 2ND STREET, SUITE 350 SAN FRANCISCO CA 94107 0 0 1 0 0001790778 5AM Opportunities I (GP), LLC 501 2ND STREET, SUITE 350 SAN FRANCISCO CA 94107 0 0 1 0 0001219014 ROCKLAGE SCOTT M 501 2ND STREET, SUITE 350 SAN FRANCISCO CA 94107 0 0 1 0 0001598549 Schwab Andrew J. 501 2ND STREET, SUITE 350 SAN FRANCISCO CA 94107 0 0 1 0 Common Stock 2020-06-30 4 C 0 513757 A 513757 I footnote Common Stock 2020-06-30 4 C 0 1997946 A 2511703 I footnote Common Stock 2020-06-30 4 C 0 999980 A 3511683 I footnote Common Stock 2020-06-30 4 C 0 799984 A 799984 I footnote Common Stock 2020-06-30 4 P 0 294117 17.00 A 1094101 I footnote Series Seed Preferred Stock 2020-06-30 4 C 0 10826417 0.00 D Common Stock 513757 0 I footnote Series A Preferred Stock 2020-06-30 4 C 0 42102730 0.00 D Common Stock 1997946 0 I footnote Series B Preferred Stock 2020-06-30 4 C 0 21072595 0.00 D Common Stock 999980 0 I footnote Series B Preferred Stock 2020-06-30 4 C 0 16858076 0.00 D Common Stock 799984 0 I footnote On June 30, 2020, the Series Seed Preferred Stock converted into Common Stock on a 21.073-for-1 basis upon the closing of the Issuer's initial public offering without payment of consideration. The Series Seed Preferred Stock was convertible at any time at the holder's election and automatically upon the closing of the Issuer's initial public offering. The shares had no expiration date. Shares are held directly by 5AM Ventures V, L.P. ("Ventures V"). 5AM Partners V, LLC is the general partner of Ventures V and may be deemed to have sole investment and voting power over the shares held by Ventures V. Each of Andrew Schwab, Dr. Kush Parmar and Dr. Scott Rocklage is a Managing Member of 5AM Partners V, LLC, and may be deemed to have shared voting and dispositive power over the shares held by Ventures V. Therefore, each of Andrew Schwab, Dr. Kush Parmar, Dr. Scott Rocklage, and 5AM Partners V, LLC may be deemed to beneficially own the shares held by Ventures V, and each disclaims beneficial ownership over the shares held by Ventures V except to the extent of his or its pecuniary interest therein. On June 30, 2020, the Series A Preferred Stock converted into Common Stock on a 21.073-for-1 basis upon the closing of the Issuer's initial public offering without payment of consideration. The Series A Preferred Stock was convertible at any time at the holder's election and automatically upon the closing of the Issuer's initial public offering. The shares had no expiration date. On June 30, 2020, the Series B Preferred Stock converted into Common Stock on a 21.073-for-1 basis upon the closing of the Issuer's initial public offering without payment of consideration. The Series B Preferred Stock was convertible at any time at the holder's election and automatically upon the closing of the Issuer's initial public offering. The shares had no expiration date. 5AM Opportunities I (GP), LLC is the general partner of 5AM Opportunities I, L.P. ("Opportunities I") and may be deemed to have sole investment and voting power over the shares held by Opportunities I. Each of Andrew Schwab and Dr. Kush Parmar is a Managing Member of 5AM Opportunities I (GP), LLC, and may be deemed to have shared voting and dispositive power over the shares held by Opportunities I. Therefore, each of Andrew Schwab, Dr. Kush Parmar and 5AM Opportunities I (GP), LLC may be deemed to beneficially own the shares held by Opportunities I, and each disclaims beneficial ownership over the shares held by Opportunities I except to the extent of his or its pecuniary interest therein. Shares are held directly by Opportunities I. /s/ Scott M. Rocklage, Managing member of the General Partner of 5AM Ventures V, L.P. 2020-07-02 /s/ Scott M. Rocklage, Managing Member of 5AM Partners V, LLC 2020-07-02 /s/ Andrew J. Schwab, Managing Member of the General Partner of 5AM Opportunities I, L.P. 2020-07-02 /s/ Andrew J. Schwab, Managing Member of 5AM Opportunities I (GP), LLC 2020-07-02 /s/ Scott M. Rocklage 2020-07-02 /s/ Andrew J. Schwab 2020-07-02