Stock-Based Compensation (Tables)

9 Months Ended

Sep. 30, 2022

Stock-Based Compensation

Schedule of activity relating to RSUs

	Number of
	shares
Outstanding as of January 1, 2022	—
Granted	122
Forfeited	(3)
Outstanding as of September 30, 2022	119

Schedule of Stock Option Activity

	Number	Weighted average
	of	exercise
	shares	price per share
Outstanding as of January 1, 2022	4,000	$	18.89
Granted	1,204	$	15.10
Forfeited	(206)	$	28.49
Cancelled	(90)	$	52.86
Exercised	(43)	$	5.41
Outstanding as of September 30, 2022	4,865	$	17.04
Options vested and exercisable as of September 30, 2022	3,037	$	12.58

Schedule of stock-based compensation charges

	Three Months Ended September 30,				Nine months ended September 30,
	2022		2021		2022		2021
Research and development	$	1,105	$	951	$	3,310	$	5,155
Selling, general and administrative		3,378		3,934		9,480		12,064
Total	$	4,483	$	4,885	$	12,790	$	17,219

PSUs

Stock-Based Compensation

Schedule of Valuation Assumptions

	Profit share unit valuation inputs
Expected volatility	94.6	%
Risk-free rate of interest	4.0	%
Expected dividend yield	—	%
Expected term	5.8	years

Stock options

Stock-Based Compensation

Schedule of Valuation Assumptions

	Nine months ended						Nine months ended
		September 30, 2022					September 30, 2021
Expected term		5.5	years	-	6.1	years	5.5	years	-	6.2	years
Expected stock price volatility		92.7	%	-	96.9	%	95.0	%	-	98.0	%
Risk-free rate of interest		1.5	%	-	3.6	%	1.0	%	-	1.2	%
Expected dividend yield		0.0	%	-	0.0	%	0.0	%	-	0.0	%