X0306 4 2019-01-17 0 0001103021 BIODELIVERY SCIENCES INTERNATIONAL INC BDSI 0001720772 Coelho Mary Theresa C/O BIODELIVERY SCIENCES INTL, INC. 4131 PARKLAKE AVE. SUITE 225 RALEIGH NC 27612 0 1 0 0 See Remarks Restricted Stock Units 0.00 2019-01-17 4 A 0 55000 0.00 A 2022-01-17 Common Stock 55000 55000 D Stock Options (right to buy) 3.73 2019-01-17 4 A 0 107109 0.00 A 2029-01-17 Common Stock 107109 107109 D The Restricted Stock Units ("RSUs") were issued to the Reporting Person on January 17, 2019, pursuant to a grant under the Issuer's 2011 Equity Incentive Plan, as amended (the "Plan"). The award is subject to time-based vesting and will vest in equal portions on: (i) January 15, 2020; (ii) January 15, 2021; and (iii) January 15, 2022. Upon vesting, each RSU entitles the Reporting Person to one share of the Issuer's common stock. The Reporting Person has been granted the right to elect to defer actual payment of a vested RSU award, subject to compliance with Internal Revenue Code Section 409A. The exercise price of the stock options issued to the Reporting Person is the volume-weighted average price of the Company's common stock for the 30-day period ending on January 16, 2019. The stock options were issued to the Reporting Person on January 17, 2019, pursuant to a grant under the Plan. The award is subject to time-based vesting and will vest in equal portions on: (i) January 15, 2020; (ii) January 15, 2021; and (iii) January 15, 2022. Chief Financial Officer and Treasurer /s/ Mary Theresa Coelho 2019-01-18