X0306 4 2020-07-28 1 0001693011 Inozyme Pharma, Inc. INZY 0001680200 Sofinnova Venture Partners X, L.P. 3000 SAND HILL ROAD, 4-250 MENLO PARK CA 94025 0 0 1 0 0001680194 Sofinnova Management X, L.L.C. 3000 SAND HILL ROAD, 4-250 MENLO PARK CA 94025 0 0 1 0 0001245624 HEALY JAMES 3000 SAND HILL ROAD, 4-250 MENLO PARK CA 94025 0 0 1 0 0001720685 Katabi Maha 3000 SAND HILL ROAD, 4-250 MENLO PARK CA 94025 0 0 1 0 0001202793 POWELL MICHAEL 3000 SAND HILL ROAD, 4-250 MENLO PARK CA 94025 0 0 1 0 Common Stock 2020-07-28 4 C 0 1590808 A 1590808 D Common Stock 2020-07-28 4 P 0 437500 16.00 A 2028308 D Series A-2 Convertible Preferred Stock 2020-07-28 4 C 0 11888112 0.00 D Common Stock 1590808 0 D On July 28, 2020, the Series A-2 Convertible Preferred Stock automatically converted into Common Stock on a 7.4730-for-1 basis upon the closing of the Issuer's initial public offering without payment of consideration. The Series A-2 Convertible Preferred Stock was convertible at any time at the holder's election and automatically upon the closing of the Issuer's initial public offering. The shares had no expiration date. The shares are held directly by Sofinnova Venture Partners X, L.P. ("SVP X"). Sofinnova Management X, L.L.C. ("SM X") is the general partner of SVP X and may be deemed to have sole voting, investment and dispositive power with respect to the shares held by SVP X. James I. Healy, Maha Katabi, and Michael F. Powell are the managing members of SM X and may be deemed to have shared voting, investment and dispositive power with respect to the shares held by SVP X. Each of the reporting persons disclaims beneficial ownership of such securities, except to the extent of his, her or its proportionate pecuniary interest therein. /s/ Nathalie Auber, as attorney-in-fact for Sofinnova Venture Partners X, L.P. 2020-07-28 /s/ Nathalie Auber, as attorney-in-fact for Sofinnova Management X, L.L.C. 2020-07-28 /s/ Nathalie Auber, as attorney-in-fact for James I. Healy 2020-07-28 /s/ Nathalie Auber, as attorney-in-fact for Maha Katabi 2020-07-28 /s/ Nathalie Auber, as attorney-in-fact for Michael F. Powell 2020-07-28