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Condensed Consolidated Statements of Cash Flows (Unaudited) - USD ($)
3 Months Ended
Mar. 31, 2019
Mar. 31, 2018
Operating activities:    
Net loss $ (11,069,000) $ (9,859,000)
Adjustments to reconcile net loss to net cash used in operating activities:    
Accretion on marketable securities (247,000)  
Depreciation and amortization expense 27,000 9,000
Stock-based compensation expense 663,000 1,181,000
Changes in operating assets and liabilities:    
Restricted cash   (84,000)
Prepaid expenses and other current assets (81,000) (264,000)
Accounts payable 144,000 80,000
Accrued liabilities (1,482,000) 1,105,000
Funding advance   500,000
Other liabilities (4,000) 28,000
Net cash used in operating activities (12,049,000) (7,304,000)
Investing activities:    
Purchases of property and equipment (24,000) (278,000)
Maturities of marketable securities 42,500,000  
Purchases of marketable securities (77,104,000)  
Net cash used in investing activities (34,628,000) (278,000)
Financing activities:    
Proceeds from public offering, net of issuance costs 46,816,000 89,938,000
Net cash provided by financing activities 46,816,000 89,938,000
Net increase in cash and cash equivalents 139,000 82,356,000
Cash and cash equivalents at beginning of period 7,042,000 53,349,000
Cash and cash equivalents at end of period 7,181,000 135,705,000
Supplemental disclosure of non-cash investing and financing activities:    
Purchases of property and equipment included in accounts payable   8,000
Conversion of redeemable convertible preferred stock into common stock   $ 81,620,000
Issuance costs associated with public offering included in accounts payable $ 231,000