Segment Reporting - Summary of Company's segment information (Details) - USD ($) $ in Thousands		12 Months Ended
		Dec. 31, 2024	Dec. 31, 2023
External program expenses for product candidates
Total External Program Expenses For Product Candidates, Total		$ 23,421	$ 30,294
Non-program specific expenses	[1]	12,085	13,412
Personnel-related expenses (including stock-based compensation)	[2]	62,163	61,169
Depreciation		6,468	6,098
Professional services and consulting fees		7,339	6,042
Facilities and infrastructure expenses		8,560	9,890
Other segment expense	[3]	7,579	5,671
Goodwill impairment		0	19,462
Interest income		(10,714)	(9,978)
Other expense, net		221	598
Income tax provision		0	0
Net loss		(117,122)	(142,658)
ADI-001
External program expenses for product candidates
Total External Program Expenses For Product Candidates, Total		17,756	26,305
ADI-270
External program expenses for product candidates
Total External Program Expenses For Product Candidates, Total		4,474	1,010
Other programs
External program expenses for product candidates
Total External Program Expenses For Product Candidates, Total	[4]	$ 1,191	$ 2,979

[1] Relates to platform research and development expenses which are not attributed to specific programs.

[2] Relates to personnel-related expenses including non-cash stock-based compensation for the years ended December 31, 2024 and 2023 of $22.2 million and $20.3 million.

[3] Relates to other expenses primarily for software subscriptions and licenses, office expenses, travel and entertainment, director compensation and recruiting fees.

[4] Relates to programs that have been discontinued or are currently in the research stage.